Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This article reviews the regulation of gene expression and assembly of intermediate filaments but presents no new findings.

This review highlights that bariatric surgery can increase nutritional deficiencies in morbidly obese patients, with particular emphasis on the risks of deficiency due to reduced food intake and malabsorption.

This study suggests that inorganic magnesium silicate sprays can improve burn wound repair and promote regeneration of skin appendages, showing superior results compared to commercial wound healing products in animal models.

Hirsute women with ovarian-sourced hirsutism are more likely to have irregular periods, with higher BMI and altered hormone ratios.

This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.

This narrative review examines the interactions between skin stem cells and their niches, finding new insights from advancements in genetic and imaging tools but reporting no new experimental results.

This review discusses the multifaceted roles of neurotrophins, especially nerve growth factor (NGF), in the development and function of nociceptors and reports no new clinical results.

This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.

This study reports a less invasive method for detecting human clock gene expression using hair follicle cells, which accurately reflects individual behavioral rhythms and suggests a time lag issue for rotating shift workers.

This review discusses the role of mitochondria and evaluates methodologies for assessing mitochondrial function and toxicity, particularly in the context of HIV and antiretroviral treatments, but it reports no new empirical findings.

In this study, the researchers found that a keratin hydrogel filler in nerve conduits led to earlier Schwann cell migration and improved cellular behaviors compared to other fillers in a rat sciatic nerve model.

This review discusses recent evidence on how night-shift work affects the circadian system, sleep, and alertness in shift workers, and reports no clinical results; potential impacts on health are considered.

This study highlights that prolonged voriconazole use is linked to an increased risk of aggressive cutaneous malignancies like squamous cell carcinoma, necessitating careful monitoring of drug levels to manage adverse effects.

This study found that peripheral clock genes, particularly BMAL1 and Period1, modulate human hair follicle cycling, suggesting their potential as therapeutic targets for affecting hair growth.

This study found that inhibiting neurosteroidogenesis affected GABA A receptor-mediated synaptic inhibition in immature rats but not in adults, suggesting age-dependent modulation of synaptic strength in the spinal dorsal horn.

Tofacitinib helped regrow hair in people with severe alopecia, but side effects occurred and benefits stopped after treatment ended.

This study developed an animal model that recreates alopecia areata by injecting healthy human skin grafts in immunocompromised mice with peripheral blood mononuclear cells enriched for NKG2D+ and CD56+ cells.

This study found that using a keratin hydrogel scaffold as a filler in collagen nerve conduits significantly improved nerve regeneration and motor recovery in Macaca fascicularis monkeys compared to saline.

This report documents two cases of severe systemic poisoning from heavy metals after short-term use of traditional Chinese medicines for treating damaged or infected tissue.

This study suggests that cultured hair follicle dermal sheath cup cells exhibit immune privilege properties, partly through the expression of PD-L1, which impacts co-cultured immune cells' behavior.

In this study, reduced androgen receptor gene methylation and shorter CAG repeats in children with premature pubarche may lead to increased hair follicle sensitivity to steroid hormones, potentially causing early pubic hair development.

Apremilast may help treat hair loss in alopecia areata.

This study found that long-term weekly administration of docetaxel is feasible at doses up to 45 mg/m² per week with acceptable toxicity, and suggests further evaluation with 40 mg/m² for phase II studies.

This study identified a novel G207E STING mutation associated with severe inflammatory symptoms and suggested that common polymorphisms in TMEM173 and IFIH1 may modify the phenotype in affected individuals.

In this case series, four adults developed severe, disabling multisymptom illness potentially linked to fluoroquinolone use, which persisted and progressed even after discontinuation of the drug.

This article discusses the role of growth hormone, insulin, and IGF-1 in acne development and highlights how diet and syndromic evidence support their involvement, but presents no new clinical findings.

Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.

This letter discusses observations of indinavir's effects on skin, likening them to those of retinoids, but does not present new clinical findings.

This review discusses the definition, pathogenesis, diagnosis, and management of hirsutism and reports no new clinical results.