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Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Polymeric nanoparticles show promise for treating skin diseases.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.