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Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Testosterone's muscle-building effects do not require its conversion to DHT.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Finasteride may cause long-lasting sexual side effects.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Imiquimod 5% cream reduced equine sarcoids in most cases.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Skin problems are very common in people with end-stage kidney disease.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Sexual activity can spread T. interdigitale, needing quick antifungal treatment to avoid permanent scarring.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.