December 2017 in “PubMed” This review examines low-level laser therapy as a potential treatment for androgenetic alopecia, presenting current clinical findings, proposed mechanisms, and rare side effects, but does not report new results.
This study found that P144 (Disitertide) significantly reduced collagen deposition and improved muscle organization in a rabbit model of post-radiotherapy fibrosis, suggesting potential antifibrotic effects.
75 citations
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August 2003 in “International journal of cosmetic surgery and aesthetic dermatology” This study found that low level laser therapy with a HairMax LaserComb improved hair counts and tensile strength in patients with androgenetic alopecia, particularly in males and vertex areas.
81 citations
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July 2011 in “Lasers in Medical Science” This study found that using a low-level laser comb led to hair regrowth in a mouse model of alopecia areata, while sham-treated mice showed no hair regrowth.
This review discusses the mechanisms, scientific support, and FDA clearance of photobiomodulation mask devices but reports no new research findings.
10 citations
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November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced laser particles as a new imaging probe capable of real-time tracking of thousands of individual cells in 3D tumor models, suggesting potential for advanced single-cell analyses.
2 citations
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February 2023 in “Shiraz E-Medical Journal” In this study, low-level laser therapy significantly improved the mechanical strength of bone at tooth extraction sites in rats, while neither platelet-rich plasma alone nor combined with laser affected mechanical strength or calcium content.
6 citations
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September 2025 in “Cosmetics” This study introduced laser-assisted exosome delivery and observed early signs of clinical improvement in two patients, though causality cannot be inferred from these preliminary, uncontrolled cases.
January 2019 in “Journal of clinical and cosmetic dermatology” This article discusses the potential of combining growth factor therapy with LLLT LED therapy for hair regrowth in androgenetic alopecia, but it does not report new clinical results.
May 2018 in “Journal of Cosmetic and Laser Therapy” The editorial discusses the effectiveness and safety of various laser and energy-based cosmetic treatments.
September 2025 in “Acta Medica International” In this study, a triple wavelength laser was found to be highly effective and well-tolerated for reducing hair in Indian women with Fitzpatrick skin types III and IV, achieving an average hair count reduction of 86.5%, with only mild and transient adverse effects observed.
August 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the history and evolution of techniques for detecting bioelectromagnetic emissions from living tissues, exploring potential medical applications, but does not present new experimental results.
February 2024 in “Neurophotonics” This review highlights the potential of transcranial photobiomodulation (tPBM) as a non-invasive and affordable treatment for brain diseases, summarizing recent advances and successful protocols based on over two decades of research.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this case study, a 26-year-old female with PLEC mutations and features of muscular dystrophy and myasthenia gravis showed significant improvement in symptoms following steroid treatment.
This study found that low-level laser therapy may effectively stimulate hair growth in adults with androgenic alopecia, but further research is needed to confirm its long-term clinical effectiveness.
This review of existing literature reports that photobiomodulation shows high effectiveness and safety in treating dermatological conditions like acne, psoriasis, and alopecia, though standardized clinical trials are needed to further validate its therapeutic benefits.
May 2025 in “The Journal of Rheumatology” This case report suggests that a proactive physical therapy model can be effective for improving physical function and meeting exercise guidelines in patients newly diagnosed with systemic lupus erythematosus.
September 2021 in “CRC Press eBooks” This review discusses the clinical and trichoscopic features of lichen planopilaris and notes its potential underdiagnosis prior to hair transplant, but it reports no new findings.
6 citations
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October 2020 in “Actas Dermo-Sifiliográficas” This review discusses the effectiveness of low-level laser therapy for androgenetic alopecia, finding significant increases in hair density and growth for individuals treated with this method.
11 citations
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January 2022 in “Journal of Healthcare Engineering” In this study, PRP and Yifu combined with ultrapulsed CO2 lattice laser were found to improve sunken acne scars more effectively than laser alone, enhancing patients' quality of life and reducing adverse events, with a higher effective rate compared to the laser-only group.
September 2022 in “The American Journal of Dermatopathology” This study found that IL-17 expression was significantly higher in perifollicular fibrosis of active Lichen planopilaris lesions, suggesting that targeting IL-17 could impact the disease's progression.
January 2025 in “Advances in Clinical Medicine” This source highlights that fractional CO2 laser, as a minimally invasive technology, shows significant benefits in treating various skin and mucosal conditions by improving therapeutic outcomes, shortening recovery times, and enhancing precise personalized interventions through emerging technologies like AI and biomarker monitoring.
February 2023 in “International journal of research - granthaalayah” This article reviews a tabletop microscopy method for recording electromagnetic radiation from tissues, using hair follicles as a model, and presents no new clinical findings.
7 citations
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January 2020 in “International Journal of Molecular Sciences” This study found that exposure to extremely low-frequency electromagnetic fields at specific intensities significantly enhanced human hair follicle cell activation and proliferation, suggesting a potential new treatment approach for alopecia.
In this study, PDLLA treatment in middle-aged mice was observed to enhance hair growth by increasing macrophage M2 polarization and hair follicle stem cell proliferation, potentially rejuvenating the skin's microenvironment and offering a novel approach for age-related hair loss.
December 2025 in “JURNAL ILMU KEDOKTERAN DAN KESEHATAN” This study reported that a 29-year-old woman with telogen effluvium experienced improved hair growth and reduced hair loss through 12 sessions of plum blossom acupuncture combined with electroacupuncture, as evidenced by new hair growth, improved hair-pull test results, and decreased telogen phase hair percentage.
12 citations
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March 2019 in “Lasers in Surgery and Medicine” This study found that low-level laser therapy increased the expression of proteins in dermal papilla tissues, suggesting it promotes hair growth in male androgenetic alopecia patients.
January 2021 in “Journal of Allergy and Therapy” This article reviews the phases of hair growth and differences between androgenetic alopecia and telogen effluvium but provides no new clinical findings on Electric Follicle Stimulation.
14 citations
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May 2018 in “Journal of the American Academy of Dermatology” This paper reviews treatments for lichen planopilaris, including low-level laser therapy, but reports no new clinical results and highlights the need for further research.
July 2016 in “Chinese Journal of Dermatology” This study found that low-level laser therapy increased hair density in men with androgenetic alopecia, with even greater improvements seen when combined with finasteride.