April 2012 in “Informa Healthcare eBooks” The document concludes that diagnosing hair loss requires evaluating multiple histological features, as no single feature is definitive on its own.
June 2024 in “British Journal of Dermatology” This case report highlights the diagnosis of folliculotropic mycosis fungoides in a 15-year-old boy with atypical skin and hair follicle changes, a rare occurrence in pediatric patients.
January 2022 in “Przegla̧d dermatologiczny” This article reviews various treatment options for diseases associated with cicatricial alopecia but reports no new clinical results.
November 2025 in “The Journal of Immunology” This study identified specific genes upregulated in skin γδ T cells involved in alopecia areata, with findings suggesting these cells contribute to disease pathogenesis through inflammatory and Th1 response mechanisms in mouse and possibly human skin.
December 2020 in “Jurnal RSMH Palembang (Online)” This case report described a 50-year-old male with end-stage renal disease who experienced improvement in his black dot tinea capitis after treatment with griseofulvin and ketoconazole shampoo.
The document concludes that hair loss in women is complex, often linked to aging, health conditions, and nutritional deficiencies, and emotional impacts should not be underestimated.
July 2026 in “Journal of King Saud University - Computer and Information Sciences” This study introduced a novel framework that significantly improves the accuracy of alopecia areata lesion segmentation in semi-supervised scenarios, outperforming existing methods and aiding in the disease's diagnosis, treatment, and staging, which can impact quality of life and mental well-being.
November 2025 in “Biomedicines” In this review, researchers reported that pyroptosis, a type of inflammatory cell death linked to inflammasome activity, is a key factor in the pathogenesis of alopecia areata and may present new therapeutic opportunities, though most treatments are still in early research stages.
4 citations
,
October 2018 in “Experimental Dermatology” This study suggests that diffuse alopecia areata initially involves an intense inflammatory attack during the anagen phase, progressing through different hair cycle stages with specific shedding patterns.
1 citations
,
April 2019 in “JAAD case reports” This case report presents a rare manifestation of secondary cutaneous B-cell lymphoma as erythematous macules coalescing into reticular patches on the scalp and forehead.
1 citations
,
September 2023 in “Portuguese Journal of Dermatology and Venereology” This case report describes a 50-year-old man with folliculotropic mycosis fungoides stage IB, noting trichoscopic findings like dilated follicular openings, black dots, and dystrophic hairs, which are less commonly documented in this condition, suggesting trichoscopy could aid in early diagnosis.
38 citations
,
February 2005 in “The journal of sexual medicine” This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.
37 citations
,
May 2016 in “Deutsches Arzteblatt International” This review outlines various causes and manifestations of hair loss, highlighting that each type has distinct underlying mechanisms and requires specific treatment approaches, without reporting new clinical results.
61 citations
,
October 2010 in “Postgraduate Medical Journal” This study found that dermatological issues, such as xerosis and pigmentation, are common in chronic kidney disease patients and increase with the severity and duration of the disease, indicating that dialysis often exacerbates these conditions.
September 2025 in “Diseases” This study found that patients with patchy alopecia areata had significantly higher serum levels of pro-inflammatory cytokines IL-6, TNF-α, IL-17A, and IL-21 compared to healthy controls, with these levels correlating positively with disease severity, age, and disease duration.
October 2023 in “Research Square (Research Square)” In this study, researchers found that patients with new-onset mild alopecia areata had higher levels of oxidative stress markers and reduced antioxidant levels compared to healthy individuals, suggesting that oxidative stress might play a role in the condition.
2 citations
,
January 2017 in “Journal of Pigmentary Disorders” This article discusses vitiligo, reviewing its symptoms, possible causes, and classification, but reports no new clinical findings.
3 citations
,
July 2020 in “International Journal of Molecular Sciences” This study reported that molecules from Zebrafish embryo cell differentiation can counteract neurodegeneration, regenerate tissues, and potentially reverse hair follicle damage in androgenetic alopecia.
130 citations
,
February 2018 in “Journal of Investigative Dermatology” This study found that tofacitinib led to ≥50% hair regrowth in eight out of twelve patients with moderate to severe alopecia areata, suggesting a potential benefit for using JAK inhibitors in treating this condition.
151 citations
,
May 2021 in “Frontiers in Medicine” This systematic review observed that a significant number of COVID-19 patients report long-term symptoms, including neurologic complaints and chronic fatigue, highlighting the presence of "post-COVID syndrome.
October 2024 in “Journal of the Endocrine Society” A woman experienced fluctuating thyroid conditions and eye disease, but her symptoms improved with treatment.
13 citations
,
December 2001 in “Dermatologic therapy” This review discusses the clinical presentations of alopecia areata, introduces guidelines for treatment studies, and explores potential changes in cutaneous innervation, but reports no new clinical results.
3 citations
,
May 2025 in “Carbohydrate Polymers” In this study, researchers developed a dissolvable microneedle patch containing baricitinib for alopecia areata treatment, reporting significantly higher hair growth in mouse models compared to controls, suggesting its potential as an effective, pain-free topical therapy.
The document concludes that most hair loss treatments don't work, balding isn't caused by dandruff, and hair loss may indicate serious health issues that require medical attention.
3 citations
,
November 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses the evolving landscape of dermatology, highlighting challenges pharmaceutical companies face with novel drug development, while smaller dermatology-focused companies lead in innovation; it reports no new results.
148 citations
,
December 2018 in “Journal of autoimmunity” This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
95 citations
,
December 1980 in “The New England Journal of Medicine” Minoxidil helped bald patient regrow hair.
30 citations
,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” This review proposes a classification system for childhood hair loss based on clinical appearance, age of onset, and associated symptoms, but reports no new clinical results.
2 citations
,
September 2025 in “Antioxidants” This review highlights that nano-antioxidants show promise as a treatment strategy for immune-mediated inflammatory diseases, like autoimmune and chronic inflammatory conditions, due to their improved stability and targeted delivery, but notes that further research is necessary to optimize their use and assess long-term safety.
January 2008 in “Dialnet (Universidad de la Rioja)” This review describes the clinical, trichoscopic, and histopathological features of hair disorders linked to autoimmune diseases and reports no new clinical results.