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Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Patients with PCOS rate their hirsutism higher than clinicians, and these self-ratings are more closely related to their quality of life and risk of depression.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Most cases of excessive hair growth in women are caused by polycystic ovarian syndrome and are linked to higher free testosterone levels.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.