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5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Statins may be linked to reproductive organ conditions, and their risks should be monitored.

Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Testosterone reduces key molecules needed for early pregnancy in rats.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The document concludes that managing PCOS involves lifestyle changes, medication for symptoms, and weight loss for fertility improvement.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Two teenage boys lost hair after taking a drug for growth, which was not a known side effect for kids.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Effective PCOS treatments require targeting specific signaling pathways.

PSA might help diagnose PCOS and related skin issues, but more research is needed.

Reproductive hormones play a crucial role in breast cancer development and treatment challenges.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

The document concludes that ongoing medical therapy is crucial for preventing hair loss, and surgical options can restore hair, with future treatments for hair loss being promising.

There is no significant link between insulin resistance and certain hair disorders like idiopathic hirsutism and androgenic alopecia.

Hair loss is a common side effect of hormone treatments for cancer.

Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.