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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Most medicinal plants in Mexican folklore have safe element levels, but arsenic exceeds safe limits in almost all.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Apoptosis is essential for human skin development and forming a functional epidermis.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Activating TRPV3 stops human hair growth.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Decomposed tritiated thymidine is less accurate for DNA tracing, and hair changes can indicate malnutrition.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Bimatoprost, a glaucoma medication, may also help treat hair loss.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Hair microRNAs could be effective biomarkers for diagnosing scleroderma.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.