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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.