research Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
Search
for
Sort by
Research
270-300 / 1000+ results 
research Treatment of Hyperandrogenism in Women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Curcumin Derivatives Inhibit Testicular 17β-Hydroxysteroid Dehydrogenase 3
Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.
research Medical Treatment of Hirsutism
The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
research Relative Safety and Efficacy of Finasteride for Treatment of Hirsutism
Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.
research How to Diagnose and Treat Women with Excessive Hair
Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.
research A Retrospective Review of Pediatric Alopecia Areata Cases Seen in a Tertiary Institution in Singapore
Most children with alopecia areata improved with treatment, but those with more hair loss had worse outcomes.
research Steroid Plant Hormones: Effects Outside the Plant Kingdom
Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
research Biology of Estrogens in Skin: Implications for Skin Aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research Probing Androgen Receptor Co-Factor Selectivity Profiles: A Chemical Tool to Determine Cross-Talk Between Androgen Receptor and Beta-Catenin In Vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications
PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
research Synthesis and Biological Evaluation of 4-(4-(Alkyl- and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-Steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2
The compound 4c effectively inhibits the enzyme linked to hair loss.
research Synthesis of Phenanthridin-3-One Derivatives: Non-Steroidal Inhibitors of Steroid 5-Alpha-Reductase
New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research Steroid 5α-Reductase Inhibition by Polymethoxyflavones
Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Emerging Medication for the Treatment of Male Hypogonadism
New treatments for male hypogonadism are effective and should be personalized.
research A Controlled Study of the Effects of RU58841, a Non-Steroidal Antiandrogen, on Human Hair Production by Balding Scalp Grafts Maintained on Testosterone-Conditioned Nude Mice
RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.
research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Compounding as a Current Therapeutic Option in Dermatology
Customized medications made through compounding can be beneficial for various skin conditions but require careful regulation and collaboration between doctors and pharmacists.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.
research Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research A Review on Polyherbal and Supplemental Approach to Treat Polycystic Ovarian Syndrome
Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).
research Geranylated Coumarins From Thai Medicinal Plant Mammea Siamensis With Testosterone 5α-Reductase Inhibitory Activity
Compounds from the plant Mammea siamensis may help treat hair loss.
![Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions](/images/research/2aedba8c-b0ac-4fa3-9ac7-9f375a016bba/small/15581.jpg)
research Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions
Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
research Dermo-Cosmetic Benefits of Marine Macroalgae-Derived Phenolic Compounds
Marine algae compounds may improve skin health and promote hair growth.
research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research Anti-Proliferative Effect of Terpenes on Human Prostate Cancer Cells: Natural Sources and Their Potential Role as Chemopreventive Agents
Certain natural compounds called terpenes may help prevent prostate cancer.
research Bioactivity of Fractions and Pure Compounds from Jatropha Cordata Bark Extracts
Compounds from Jatropha cordata bark have significant anti-inflammatory effects and could help with hair loss.
research Resveratrol Derivatives: A Patent Review (2009–2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.