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Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

Using neurohormones to control keratin can lead to new skin disease treatments.

Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.

Micropigmentation safely and effectively hides scalp hair loss and scars.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.

Micropigmentation effectively hides scalp scars with few complications.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

The conclusion is that accurate diagnosis of different types of hair loss requires careful examination of tissue samples and understanding of clinical symptoms.

Hair in mammals likely evolved from glandular structures, not scales.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Hormones and genes affect hair growth and male baldness.

Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.

A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.

About 20% of Japanese macaques had head alopecia, and stress and environment might cause hair loss.

Burn scars heal abnormally and more research is needed to find better treatments.

The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.