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Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Smoking may contribute to hair loss in men.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Face-lifts can lead to complications like bleeding, nerve injury, skin death, hair loss, and rare infections, with careful surgery reducing risks.

Assessing newborn scalp hair can reveal important health information.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Facial rejuvenation surgery has evolved to yield natural results with low complication rates, and more men and older patients are choosing this surgery.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.