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Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Immune activities and specific genes are important in male pattern baldness.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Finasteride may increase depression by reducing brain cell growth.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Finasteride reduces gambling symptoms in Parkinson's patients.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Finasteride doesn't affect ovulation in normal women.

Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.