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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

The Rotterdam Study aims to understand various diseases in older adults.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

PLD is an effective and safer alternative for treating breast cancer.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

Some common medications can harm male fertility, but many effects can be reversed.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.