66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
January 1989 in “Side effects of drugs annual” Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
43 citations,
November 1988 in “The Journal of Comparative Neurology” Different types of hairs on a rat's hindlimb have varying levels and patterns of nerve innervation.
[object Object] January 2013 in “The Journal of Sexual Medicine” The document suggests that finasteride may cause depression and suicidal thoughts, while prostate surgery does not harm sexual health.
35 citations,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
September 2016 in “Journal of dermatological science” Transplanted whisker follicles caused hair growth on the spine of mice.
276 citations,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
159 citations,
December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
48 citations,
January 2000 in “Hormone Research in Paediatrics” Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
[object Object] 46 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
39 citations,
April 2019 in “Journal of Biomaterials Science, Polymer Edition” RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
32 citations,
January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
29 citations,
February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Loss of Fz6 disrupts hair follicle and associated structures' orientation.
28 citations,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
15 citations,
April 2014 in “Experimental Dermatology” Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.
2 citations,
October 2022 in “Journal of Biomedical Science” Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
1 citations,
January 2018 in “Stem cell biology and regenerative medicine” DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
1 citations,
November 2017 The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
August 2024 in “International Journal of Basic & Clinical Pharmacology” Secretome-based therapies could improve hair growth better than current treatments.
January 2024 in “Archives of pharmacy practice” The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.
August 2019 in “Stem cells” New treatments for hair loss, fertility, and wound healing are being explored.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” HSD11b1 affects skin nerves and increases non-histaminergic itch.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
1113 citations,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
417 citations,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
359 citations,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.