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Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

New treatments for male hypogonadism are effective and should be personalized.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Multimodal primary treatment improves survival in premenopausal breast cancer patients and is also beneficial for postmenopausal women.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Natural products and phytochemicals may help with hair regrowth, but more research is needed.

Herbal ingredients like aloe vera and hibiscus can help with hair problems like hair loss and dandruff.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.

Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.

Excessive hair growth in women can be treated with medications like spironolactone and finasteride, and male-pattern baldness in women can be improved with similar treatments.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.