1 citations,
March 2011 in “Infertility” Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.
October 2015 in “Elsevier eBooks” Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
June 2007 in “Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii” Finasteride is effective in stopping hair loss and promoting regrowth in most men with mild side effects.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
25 citations,
May 2012 in “The Journal of Sexual Medicine” Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
56 citations,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
53 citations,
June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
56 citations,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
49 citations,
February 2009 in “Maturitas” Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.
41 citations,
December 2015 in “Journal of the European Academy of Dermatology and Venereology” The conclusion is that a new biopsy technique and humidity chamber help study skin mites better and suggest mite overpopulation may cause skin diseases.
40 citations,
December 2011 in “British Journal of Dermatology” Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.
39 citations,
January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
39 citations,
September 2013 in “Journal of Cosmetic Dermatology” Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
June 2007 in “Endocrinology and Metabolism Clinics of North America” The document covers various male health issues, their causes, treatments, and related conditions.
271 citations,
December 2005 in “New England journal of medicine/The New England journal of medicine” The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.
224 citations,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
81 citations,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
70 citations,
August 1995 in “Fertility and Sterility” Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.
65 citations,
September 2010 in “Journal of the Neurological Sciences” Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
57 citations,
February 2014 in “Experimental Dermatology” Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
53 citations,
October 1993 in “Drug Safety” Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
22 citations,
October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
18 citations,
February 2016 in “The Journal of Clinical Endocrinology and Metabolism” Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
12 citations,
May 2010 in “PubMed” No definitive link between finasteride and male breast cancer, but further research is needed.
12 citations,
February 1997 in “British Journal of Dermatology” The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
11 citations,
May 1996 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
10 citations,
May 1995 in “Journal of General Internal Medicine” Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
8 citations,
January 2017 in “Fertility and Sterility” Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.
6 citations,
August 2020 in “JCRPE” A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.
6 citations,
September 2010 in “Current Urology Reports” New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.