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The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.

Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

Finasteride helps female-pattern hair loss.

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Some common medications can harm male fertility, but many effects can be reversed.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Some chemotherapy can cause permanent hair loss.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.