November 2025 in “International Journal of Research in Medical Sciences” In this randomized, placebo-controlled study, Titagen® was found to improve skin, hair, and nail health in adults consuming 5g daily, and reduce pain and improve quality of life for osteoarthritis patients taking 10g daily, without related adverse events.
April 2016 in “Journal of The American Academy of Dermatology” People with certain allergic conditions or higher white blood cell counts have more severe hair loss, and treating hair and nail side effects early in melanoma therapy can improve quality of life.
42 citations
,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers identified two distinct homozygous mutations in the KRT85 gene among consanguineous Pakistani families with pure hair and nail ectodermal dysplasia, highlighting variations in severity and potential impacts on the K85 protein function.
2 citations
,
January 2018 in “Springer eBooks” The document explains what healthy skin, nails, and hair look like on an ultrasound.
March 2026 in “Scholars Journal of Medical Case Reports” In this study, nail involvement was observed in 42.8% of children with alopecia areata, yet often went unrecognized, indicating that clinical and dermoscopic evaluations can improve detection and provide important prognostic information.
January 2026 in “Dermatology Practical & Conceptual” This study observed that 78.3% of patients with alopecia areata exhibited nail changes detectable by dermoscopy, notably nail pitting, in contrast to 14.2% of healthy controls, with these changes significantly associated with disease severity, age, and duration.
September 2024 in “Cureus” This case report outlines a 10-year-old boy who experienced a six-year history of twenty-nail dystrophy, highlighting the importance of physical examination for early diagnosis and management of nail disorders, with his primary symptoms involving nail disfigurement and alopecia areata, but no other health issues.
September 2023 in “Cureus” This study at B.J. Medical College and Civil Hospital highlighted an extensive range of nail disorders, with onychomycosis being the most common, and emphasized the importance of nails in diagnosing both dermatological and systemic conditions.
February 2005 in “Journal of The American Academy of Dermatology” Not all nail problems are caused by fungus, new allergens are being identified, PCOS has various treatments, and aesthetic procedures like Botox are advancing.
138 citations
,
February 2007 in “European journal of cancer” This review discusses the classification, pathogenesis, and management of skin, hair, nail, and mucosal changes due to EGFR inhibitors, emphasizing the importance of informing patients to improve therapy compliance.
23 citations
,
November 2001 in “Archives of Dermatology” This review discusses recent advances in the genetic understanding of inherited hair and nail disorders and reports no new clinical results.
13 citations
,
June 2010 in “Journal of The American Academy of Dermatology” This study reports previously unreported nail features in Cronkhite-Canada syndrome, specifically recurrent onychomadesis of all 20 nails linked to systemic illness.
11 citations
,
September 2007 in “Advances in therapy” This study found that the oral supplement INVERSION® Femme significantly reduced weight and hair loss and improved skin and nails in overweight women.
8 citations
,
April 2017 in “International Journal of Dermatology” This study found that applying 5% topical minoxidil twice daily significantly increased nail growth rate in healthy participants compared to untreated nails, with effects observable from the first week.
11 citations
,
January 1985 in “British Journal of Dermatology” The document concludes that an inherited nail condition often improves on its own, and spironolactone effectively treats acne in women.
July 2018 in “British Journal of Dermatology” Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.
July 2017 in “British Journal of Dermatology” The document concludes that scalp conditions have various causes and can present in many different ways.
Robotic-assisted hair transplant is effective and less painful, but needs more evaluation for long-term results.
April 2016 in “Journal of The American Academy of Dermatology” Dutasteride is more effective than finasteride for hair growth with similar side effects.
43 citations
,
November 2007 in “Dermatologic Clinics” This article discusses various hair and nail abnormalities linked to paraneoplastic conditions and cancer treatments, emphasizing their potential role in diagnosing and managing internal malignancies and reports no new clinical findings.
18 citations
,
March 2004 in “Clinics in Dermatology” This review discusses recent advances in understanding the cellular, molecular, and genetic factors contributing to lupus erythematosus and reports no new experimental findings.
7 citations
,
December 2008 in “Expert Review of Dermatology” This article reviews hair and nail disorders in children, emphasizing their prevalence, congenital and acquired origins, and the diagnostic challenges compared to treatment, but reports no new clinical results.
May 2015 in “Journal of The American Academy of Dermatology” Povidone-iodine nail solution effectively treats nail infections caused by chemotherapy.
114 citations
,
January 2007 in “Drug Safety” This review discusses various adverse drug reactions affecting the skin, hair, and nails, emphasizing the importance of recognizing and reporting these reactions but reports no new clinical findings.
65 citations
,
January 2013 in “Cochrane library” This review found that infliximab, golimumab, and some forms of radiotherapy significantly improved nail psoriasis compared to controls, although they could have serious adverse effects and are not commonly used specifically for nail issues.
1 citations
,
July 2016 in “British Journal of Dermatology” Men with a certain type of hair loss often use facial moisturizers, and a specific antibiotic treatment may help another hair condition.
1 citations
,
July 2019 in “British Journal of Dermatology” This study found that 15% minoxidil topical solution was more effective than low-level laser therapy in improving hair regrowth and patient satisfaction in individuals with androgenetic alopecia.
21 citations
,
April 2014 in “PLoS ONE” In this study, researchers identified a novel KRT74 gene mutation associated with autosomal recessive pure hair and nail ectodermal dysplasia in a Pakistani family, expanding the known genetic causes of the disorder.
7 citations
,
May 2014 in “Clinical practice” This article reviews drug-induced hair and nail disorders and discusses their clinical recognition, underlying mechanisms, and potential treatment strategies, without presenting new research findings.
3 citations
,
January 2020 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” Cryotherapy is effective for ingrown toenails, especially in single cases, but has high recurrence in younger and bilateral cases.