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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

K6hf is a unique protein found only in a specific layer of hair follicles.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Hair shedding is an active process that could be targeted to treat hair loss.

The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

The representation of skin conditions in medical reviews partly matches their real-world impact.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.