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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

PCOS is caused by both genetics and environmental factors like diet and obesity.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.