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This study found that antisense oligonucleotides can significantly reduce androgen receptor expression in cultured human sebocytes and may offer new therapeutic possibilities for androgen-associated skin diseases.

This study reviewed the challenges of delivering nucleic acids for gene therapy, highlighting the limitations of non-viral vehicles and exploring bioinspired strategies using cell membrane camouflage for improved delivery efficacy.

In this study, a biocompatible zinc oxide nanocomposite loaded with the anticancer drug 9-Br-Nos demonstrated effective drug delivery and cytotoxicity against lung cancer cells in vitro, while also proving non-toxic to healthy cells, suggesting its potential for targeted lung cancer treatment.

In this case report, a 20-year-old man with a birthmark was identified as having a supernumerary nipple, a developmental anomaly, using dermoscopy to distinguish it from other pigmented skin lesions such as melanocytic nevus or basal cell carcinoma.

This article reviews CRISPR/Cas system delivery methods for genome editing and highlights RNA's promise in non-viral in vivo applications but reports no new clinical results.

This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.

In this case report and literature review, researchers identified a novel mutation in the CLDN1 gene linked to neonatal ichthyosis-sclerosing cholangitis syndrome and found that its phenotype varies widely, suggesting a multidisciplinary approach is crucial for management.

This study found that N-acetyl-glucosamine-loaded nanostructured lipid carriers showed promise for skin lightening in healthy volunteers by reducing melanin distribution.

This case report describes a middle-aged man with niacinamide-induced poikilodermatous flushing observed on the neck, established through clinical and dermatoscopic evaluation.

This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.

A new test helps find drugs to treat head and neck cancer by targeting c-Rel.

This case study reports a 36-year-old man with KID syndrome caused by an N14Y GJB2 mutation, expanding the mutation spectrum of this condition in the Chinese population.

This study aimed to enhance the skin penetration of brown algae fucoidan using a Nanostructured Lipid Carrier, achieving a formulation with good physical quality and stability.

This study found that poly(adenosine diphosphate-ribose) synthesis in human skin varies by cell type and condition, with distinct patterns in psoriatic, cancerous, and normal tissues.

This study reports the development of a fluorescent ionic liquid that shows high sensitivity and selectivity for detecting dextran sulfate sodium, with potential applications in clinical diagnostics and environmental monitoring.

This study found that the wavy coat trait in Nakano cataract mice is polygenic, involving major and minor genes, and resembles human curly scalp hair associated with the PRSS53 gene alteration.

This study found that NIMP-R14-conjugated nanoparticles, loaded with roflumilast, effectively targeted neutrophils to reduce inflammation and improve symptoms in a mouse model of psoriasiform dermatitis, suggesting potential for targeted therapy in autoimmune skin diseases.

In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.

This review examines the advances in nanostructured lipid carriers for treating hyperpigmentation but presents no new clinical results; the authors highlight their potential benefits and applications.

In this study, it was observed that NIPAL4 mutations linked to autosomal recessive congenital ichthyosis lead to abnormal skin barrier function due to cytotoxic effects disrupting lipid structure and organization, which topical treatments only partially ameliorated.

Slug (Snai2) helps regulate hair growth timing in mice.

In this study, induction nab-paclitaxel plus cisplatin, combined with nimotuzumab and IMRT, followed by S-1 adjuvant chemotherapy, showed excellent survival benefits with tolerable toxicities for stage N3 nasopharyngeal carcinoma patients.

This review summarizes the potential of nanostructured lipid carriers in drug delivery systems, highlighting their promise in enhancing the stability and skin penetration of anti-aging cosmetics.

This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.

This study identified altered mRNA and lncRNA profiles in NS scalp tissues, highlighting CDKN2AIP as a downregulated gene involved in a ceRNA network.

This study used Cisd2 knockout mice models and found that these mice display premature aging characteristics and an increase in dysfunctional neutrophils, suggesting Cisd2's role in calcium homeostasis and neutrophil function via interactions with Calnexin and SERCA.

This article discusses the human KRT72 wild-type allele's role in hair formation and reports no new research findings.

This study suggests that mutation-targeted siRNA therapy could potentially treat keratitis-ichthyosis-deafness syndrome by selectively reducing harmful GJB2 mutant gene expression in patient-derived keratinocytes.

This study suggests that oleosomes in Sesbania nodules are utilized for cell growth and development but are not directly involved in nitrogen fixation.