In this laboratory study, the methanolic extract of Eclipta alba demonstrated significant anthelmintic activity against earthworms (Pheretima posthuma), causing paralysis and death at doses of 50-100 mg/ml, with stronger effects observed at higher concentrations compared to the standard treatment, albendazole.
January 2015 in “Nasza Dermatologia Online” This case report describes an eight-year-old Kashmiri boy diagnosed with monilethrix, a rare genetic hair disorder, characterized by a beaded appearance and fragility of the hair shaft.
3 citations
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November 2022 in “Frontiers in Plant Science” This study found that microwave-assisted extraction significantly increased the yield of secondary metabolites, including phenolic and flavonoid content, from Nardostachys jatamansi, enhancing its anti-Alzheimer's potential compared to conventional extraction methods.
21 citations
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March 2003 in “Clinical and Experimental Dermatology” This study found two recurrent missense mutations in the hHb6 gene associated with monilethrix in families from Russia and Colombia, supporting their role in this hair disorder worldwide.
May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas” This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
21 citations
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February 1988 in “Toxicology” This study found that high doses of TCB caused severe toxicity in cotton top marmoset monkeys, with clinical and histological changes similar to those in humans and other primates exposed to PCBs.
100 citations
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November 1997 in “Human Genetics” In this study, researchers found that the prevalent Glu 410 Lys mutation in hHb6 and a new Glu 403 Lys mutation in hHb1 are linked to monilethrix, suggesting a mutational hotspot in type II hair keratins.
12 citations
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February 2022 in “Frontiers in Pharmacology” This study reports that Asparagus racemosus and Withania somnifera extracts significantly reduced paclitaxel-induced myelosuppression and morbidity in mice, suggesting their potential as therapeutic adjuvants in cancer management.
1 citations
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June 2015 in “Journal of anatomy” This study reported that novel kainate derivatives, especially ZCZ90, maintained potency in affecting proprioceptive sensory organ firing, aiding future receptor studies for potential treatment innovations.
January 2014 in “The Scientific Issues of Ternopil Volodymyr Hnatiuk National Pedagogical University Series pedagogy” This study found that an ointment containing essential oil of yarrow floodplain shows a pronounced healing effect and stimulates hair growth on damaged skin.
3 citations
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January 2024 in “3 Biotech” This study provides detailed taxonomic and pharmacognostic analyses to authenticate and standardize seven herbal medicines, aiding in their differentiation from common adulterants for improved identification and classification.
84 citations
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April 2013 in “Applied Microbiology and Biotechnology” This review discusses the current research and development of mannosylerythritol lipids, particularly focusing on their potential commercial applications in cosmetics; it reports no new results.
16 citations
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September 2022 in “International Journal of Molecular Sciences” This study reported that Juniperus sabina needle extract showed significant anti-butyrylcholinesterase activity, suggesting potential medicinal value due to high podophyllotoxin levels.
22 citations
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February 2008 in “Journal of Neurochemistry” This study found that minoxidil prevents long-term serotonergic toxicity induced by MDMA in rats, primarily by opening mitochondrial KATP channels and involving Akt and MAP kinases in its neuroprotective mechanism.
September 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This source compiles information on Calotropis gigantea, an Asclepiadaceae plant used in traditional medicine for treating conditions like leprosy, asthma, vertigo, and hair loss, highlighting its diverse medicinal potential.
This study found that while Smilax aristolochiifolia continues to hold socio-economic importance within the Totonac culture in Puebla, low abundance and land use changes pose challenges to its conservation.
1 citations
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January 2003 Merkel cells likely attract sensory nerve fibers.
1 citations
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January 2019 in “PubMed” The authors describe a case of pityriasis amiantacea in a woman following bone marrow transplantation, potentially linked to melphalan conditioning, which responded to treatment with mineral oil and specific shampoos.
January 2013 in “The Pan African medical journal” This report describes two cases of monilethrix in Afghan siblings, detailing the hair disorder's clinical presentation and potential influences on hair growth, such as hormonal changes and iron supplementation.
February 2018 in “Open MIND” This study found that both Glycyrrhiza glabra and Emblica officinalis extracts demonstrated significant antibacterial activity against Escherichia coli, with the highest effect seen in 100% crude extracts.
1 citations
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November 2013 in “Asian Journal of Pharmaceutical and Clinical Research” In this study, the medicated oil made from Martynia annua leaves showed strong hair growth-promoting activity in a mouse model of testosterone-induced alopecia, potentially outperforming the standard treatment, finasteride.
May 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the peach gene CTG134, involved in auxin-ethylene interactions, plays a role in hormonal regulation during root hair formation in Arabidopsis and tobacco.
82 citations
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April 2014 in “Plant Cell & Environment” This study found that magnesium supply significantly influences root hair development in Arabidopsis, affecting reactive oxygen species, calcium signaling, and the expression of genes associated with root hair growth.
January 2019 in “Global Dermatology” This review discusses the genetic disorder, monilethrix, characterized by fragile, brittle hair and its inheritance patterns, and reports no new clinical results.
17 citations
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January 1998 in “Neurourology and Urodynamics” This report describes a case of adrenomyeloneuropathy where neurogenic bladder dysfunction developed, attributed to demyelinating lesions in the patient's peripheral nerves, spinal cord, and cerebral white matter.
This study observed that stimulating the cholinergic system via muscarinic receptors in dermal papilla cells and other hair-related tissues promoted hair growth, with mechanisms involving the activation of Wnt/β-catenin signalling pathways in cell cultures and increased hair shaft elongation in mouse vibrissae treated with bethanechol.
13 citations
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November 2017 in “Neurotoxicity research/Neurotoxicity resarch” This study found that sodium metabisulfite activates sodium channels and increases cellular excitability and excitotoxicity in both cardiomyocyte and neuron models, which exacerbates seizures and neuronal damage in rats.
June 2020 in “International journal of medical science and clinical invention” This review discusses the uses of Achillea millefoilum described by Ibn Rushd, finding scientific support for its applications in treating alopecia and skin disorders.
1 citations
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October 2010 in “Series in cosmetic and laser therapy” Mesotherapy is a minimally invasive treatment with potential benefits and risks, requiring standardized practices and further investigation.