research FDA Declines Approval of Testosterone Drug for Third Time
The FDA did not approve a testosterone drug because of safety concerns.
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research Popliteal Artery Entrapment Syndrome (PAES) — A Case Report on Differential Diagnosis of Intermittent Claudication
Popliteal Artery Entrapment Syndrome (PAES) is a rare but possible cause of leg pain during walking, even in untrained women.
research Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches
Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
research The Action of Diazoxide and Minoxidil Sulphate on Rat Blood Vessels: A Comparison with Cromakalim
Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
research Hair Organ Regeneration Via Bioengineered Hair Follicular Unit Transplantation
Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
research The Repairing of Full-Thickness Skin Deficiency and Its Biological Mechanism Using Decellularized Human Amniotic Membrane as the Wound Dressing
Human amniotic membrane helps heal skin wounds faster and with less scarring.
research The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit
Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.
research Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture
Researchers created hair-inducing human cell clusters using a 3D culture method.
research Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician?
Recognizing the different stages of alopecia areata is crucial for accurate diagnosis and treatment.
research Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action
Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.
research Melatonin Promotes Cashmere Goat (Capra Hircus) Secondary Hair Follicle Growth: A View from Integrated Analysis of Long Non-Coding and Coding RNAs
Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
research Platelet-Rich Plasma for Androgenic Alopecia Treatment: A Comprehensive Review
PRP shows promise for treating hair loss but needs more research.
research Antiandrogenic Activities of Glycyrrhiza Glabra in Male Rats
Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.
research How Can Frey's Syndrome Be Prevented or Treated Following Parotid Surgery?
Botulinum toxin type A injections are the preferred treatment for Frey's syndrome after parotid surgery.
research The Prevention of Benign Prostatic Hyperplasia (BPH)
A vaccine may prevent benign prostatic hyperplasia (BPH).
research Endoplasmic Reticulum Stress at the Crossroads of Progeria and Atherosclerosis
A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.
research Molecular and Spatial Landmarks of Early Mouse Skin Development
The research maps the complex development of early mouse skin, identifying diverse cell types and their roles in forming skin layers and structures.
research Hidradenitis Suppurativa: A Folliculotropic Disease of Innate Immune Barrier Dysfunction?
Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
research The Microanatomy of Human Skin in Aging
Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
research Molecular and Spatial Design of Early Skin Development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Finasteride Adverse Effects and Post-Finasteride Syndrome: Implications for Dentists
Finasteride, used for treating hair loss, can cause mental, physical, and sexual side effects, some of which may persist even after stopping the drug, and it can also cause mild to moderate oral issues.
research Comment on Scalp Neuropathy in Androgenetic Alopecia
Hair loss in men (androgenetic alopecia) is significantly linked to decreased scalp sensitivity, but not temperature sensitivity. More research is needed to confirm this. Comparing this hair loss to leprosy is unsupported and stigmatizing.
research Scalp Neuropathy in Androgenetic Alopecia
Scalp nerve issues are linked to hair loss in men.
research Low-Dose In Utero Exposure to Finasteride Promotes Developmental Changes in Both Male and Female Gerbil Prostates
Exposure to low doses of finasteride in the womb causes changes in the prostate of both male and female gerbils.
research Embryology, Histology, and Physiology of the Hair Follicle
The document explains how hair follicles develop, their structure, and how they grow.
research Effect of Mesenchymal Stem Cells in Androgenic Induced Alopecia in Adult Male Albino Rats Versus Conventional Minoxidil Treatment
The study investigated the effects of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) compared to conventional minoxidil treatment on androgenic alopecia (AGA) in 48 adult male albino rats. Results showed that stem cell therapy was more effective than minoxidil in treating AGA, as evidenced by changes in hair follicle dynamics, including a decrease in terminal hair number and an increase in vellus hair. Additionally, there were structural changes such as cavitations in hair and sheaths, collagen fiber deposition, and thinning of the arrector pili muscle. Overall, stem cell therapy demonstrated superior efficacy in promoting hair growth in AGA.
research New Histopathological Findings in Scarring Alopecias
New findings may help diagnose and understand scarring alopecia better.
research Evaluation of Morphological and Histological Changes in Transplanted Hair Follicles
Transplanted hair follicles show significant changes after FUE, needing more research.
research Dihydrotestosterone Induces Arterial Stiffening in Female Mice
Dihydrotestosterone increases arterial stiffness in female mice without changing blood pressure or aortic wall thickness.
research 4-Aminopyridine Promotes Accelerated Skin Wound Healing via Neurogenic-Mediator Expression
4-aminopyridine, a FDA-approved drug, speeds up skin wound healing and tissue regeneration.