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Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

Minoxidil boosts hair growth by increasing cell production and survival.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Too much androgen can cause hair loss; finasteride may help.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Hair follicles may soon be used more for targeted and systemic drug delivery.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

Tempol is safe and may prevent hair loss from brain radiotherapy.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.