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In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.

This chapter reviews various in vitro and laboratory animal models for studying potential therapies for alopecia and reports no new results.

This study suggests that mutation-targeted siRNA therapy could potentially treat keratitis-ichthyosis-deafness syndrome by selectively reducing harmful GJB2 mutant gene expression in patient-derived keratinocytes.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

This study found a statistically significant increase in glycosylated hemoglobins among patients with adult-acquired panhypopituitarism undergoing long-term GH replacement therapy, with two developing diabetes requiring treatment.

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

This review discusses the physiopathology of androgenetic alopecia and evaluates various traditional and emerging treatments, reporting no new clinical results but highlighting the need for enhanced treatment strategies.

This article reviews the role of polarity proteins in epidermal morphogenesis and homeostasis and discusses how their alteration may contribute to skin disease, but reports no new experimental findings.

This article explores the endocrine functions involved in the pathogenesis of polycystic ovarian syndrome and discusses approaches for diagnosing and managing the condition, with no new clinical results reported.

This study revealed that chronic restraint stress in mice led to significant alterations in metabolic pathways and gene expression associated with hair growth inhibition, using metabolomics and transcriptomics analyses.

This study developed a method to culture and maintain chicken feather follicles in vitro, preserving structure and biology similar to their in vivo state, though some gene expression was altered.

This study found that metabolic syndrome negatively affected the response to intradermal dutasteride injection in female pattern hair loss, with participants showing reduced terminal hair and increased vellus hair compared to those without the syndrome.

The researchers reported that zinc carbonate nanoparticles stabilized with polyvinylpyrrolidone did not show local irritant or skin-resorptive effects in preclinical tests on rabbits and rats.

This study found that restoring the skin microbiome significantly improved hair growth and skin condition in androgenic alopecia model mice by modulating the immune-inflammatory balance, highlighting the potential of bacterial-based therapies for hair loss.

This consensus highlights that addressing nutritional and endocrine deficiencies through lifestyle modifications, nutritional support, and medical interventions is crucial for managing hair loss associated with endocrine and gynecological disorders, emphasizing the need for a multidisciplinary approach involving dermatologists, nutritionists, endocrinologists, and gynecologists.

This review of existing literature reports that photobiomodulation shows high effectiveness and safety in treating dermatological conditions like acne, psoriasis, and alopecia, though standardized clinical trials are needed to further validate its therapeutic benefits.

This research suggests that phytoestrogen-rich herbal extracts may help reduce hyperandrogenism, insulin resistance, and ovarian weight while promoting ovulation in polycystic ovarian syndrome, indicating potential for discovering new bioactive compounds.

In this study, researchers found that high doses of rosemary extract given to lactating mother rats adversely affected their offspring, causing weight issues and damage to liver, kidney, and testis tissues, suggesting potential teratogenic risks if used during human pregnancy and lactation.

In this study, the combination of photobiomodulation therapy and Respiro Myrtol forte reduced pain and inflammation more effectively than either treatment alone in patients after septoplasty.

In this study, xerosis was the most common skin condition found among elderly participants, followed by wrinkling and immunoglobulin heavy chain deposition.

This study suggests that co-culturing human outer root sheath cells with human dermal papilla cells can restore their ability to induce hair growth by altering gene expression through paracrine signaling.

This article reviews anti-aging strategies in dermatology, emphasizing the role of skin as a model for studying aging and promoting preventive and therapeutic interventions, but it does not present new findings.

Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.

In this study, researchers observed that heat stress significantly affected hair and skin traits in two indigenous goat breeds, with Kodi Aadu goats demonstrating greater thermal resilience compared to Kanni Aadu goats, potentially due to differences in gene expression and methylation.

This review discusses the complex correlation between cellular senescence and PCOS, emphasizing senescence markers, mechanisms, and potential anti-senescence therapies, but reports no new clinical results.

In this study, the combination of low level light therapy with arginine, arterial extract, or biotin tripeptide-1 was associated with improvements in hair density and follicle structure in androgenic alopecia.

This review discusses the challenges in diagnosing PCOS in adolescents due to overlapping symptoms with normal puberty and reports no new clinical findings, emphasizing the need for more research on treatment options.

This study suggests that myotonic dystrophies may qualify as segmental progeroid disorders due to molecular and clinical similarities with typical progeroid syndromes.

This article reviews the aging process of sebaceous glands, highlighting the role of intrinsic and extrinsic factors on their degradation and reporting no new clinical findings.

This review highlights the potential of indigenous southern African foods rich in phytochemicals and soluble dietary fibers to combat cardiovascular disease in economically disadvantaged urban populations in South Africa by improving dietary diversity and affordability.