10 citations
,
January 1985 in “PubMed” This study found that electron and proton microprobe analysis can reveal differences in element distribution within human hair and epidermis, although no significant water content differences were noted between atopic eczema and normal skin.
24 citations
,
November 1978 in “Biochemistry” This paper reports on the structural characteristics of α-type filaments in the inner root sheath cells of guinea pig hair follicles without presenting new clinical findings.
3 citations
,
September 2018 in “Journal of Structural Biology” Oxidized trichocyte keratin has a helical dislocation in its structure.
11 citations
,
January 1977 in “Archives of dermatological research” Mouse tail skin has different keratinization near hair follicles and scales.
4 citations
,
January 1981 in “PubMed” This study found that medullary cell content in mammal hair evolves from an amorphous form to a biphasic phase, with human and anthropoid hair containing both macrofibrils and microfibrils.
34 citations
,
September 2007 in “Experimental Dermatology” This study found that the outer protein layer of Merino wool is rich in sulfur-containing proteins similar to those found in both sheep wool and human hair.
3 citations
,
January 1998 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” This study used rapid-freezing immunocytochemistry to successfully map the ultrastructural localization of hair keratins in human scalp hair, primarily finding them in macrofibrils in the cortex and endocuticle.
11 citations
,
January 2016 in “Biointerphases” This study suggests that the outermost hair cuticle surface is rich in 18-methyleicosanic acid (18-MEA), supporting previous findings of its multilayer lipid and protein structure.
8 citations
,
March 2023 in “BMC Research Notes” This pilot study explored a new method using laser-capture microdissection and 16S rRNA gene sequencing to analyze the human scalp hair follicle microbiome more accurately, revealing region-specific variations in microbial diversity and abundance.
8 citations
,
July 2004 in “Journal of morphology” This study explored the structure and keratin composition of marsupial hairs, finding similarities in keratin localization to hairs in placental mammals, and highlighting potential roles of trichohyalin and transglutaminase during hair development and shedding.
16 citations
,
September 2006 in “The Journal of Immunology” This study identified that mouse MILL1 and MILL2 are glycoproteins distinct from human MICA/B, primarily due to their association with β2-microglobulin and TAP-independent surface expression.
30 citations
,
April 2017 in “Journal of structural biology” This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.
2 citations
,
August 1987 in “Analytical Biochemistry” This study introduced a method to isolate and separate microfibrillar proteins from human hair, identifying previously undetected glycine- and tyrosine-rich proteins.
15 citations
,
December 1972 in “Journal of Investigative Dermatology” 72 citations
,
September 1975 in “Biology of Reproduction” This study found that zinc is primarily located in the tails of mature rat sperm, associated with -S-S-bonded structures, and suggests a possible similarity in zinc interactions between sperm keratin and hair proteins.
34 citations
,
August 1966 in “Experimental cell research” This study examined developing hair cortex with electron microscopy and found that keratin fibrils form between specific regions in hair follicles and aggregate into twisted cables.
10 citations
,
December 2001 in “PubMed” This research suggests that both proposed pathways into hair fibers for molecule penetration are valid and complementary, with all fiber structures acting as potential routes for delivering materials.
30 citations
,
January 1999 in “Journal of Cutaneous Pathology” This study suggests that spiny keratoderma may be an ectopic hair formation on palms and soles, based on keratinization patterns observed using antikeratin antibodies and electron microscopy.
116 citations
,
April 1986 in “The journal of cell biology/The Journal of cell biology” This study reports that a 190,000 molecular weight protein, identified as trichohyalin, may play a matrix role in the development of inner root sheaths in hair follicles.
1 citations
,
January 2021 in “Springer Proceedings in Materials” This study demonstrates a sample preparation method for wool follicles that allows for clear keratin labeling and ultrastructural preservation in microscopy, reducing common artefacts from conventional fixation techniques.
22 citations
,
September 2001 in “Journal of Investigative Dermatology” S100A8 and S100A9 proteins help form hair shafts during growth.
1 citations
,
January 2001 in “PubMed” This study proposes that the terminal tuft structure in sensory nerve endings, involving Schwann cell processes and axon fingers, potentially plays a role in mechano-electric transduction in rats.
49 citations
,
September 2004 in “Journal of the European Academy of Dermatology and Venereology” This study found that careful light microscopy using fluid-mounted hair improves detection of the pili annulati phenotype, which varies widely in expression and affects hair fragility.
17 citations
,
December 2002 in “Biochemical and biophysical research communications” This study reports on the biochemical characteristics of S100A3 protein in human hair cuticle, notably finding its N-terminal methionine is acetylated and has a slightly lower isoelectric point compared to the recombinant version.
2 citations
,
May 2012 in “Acta pharmaceutica sinica B” This study examined the microscopic characteristics of hair or feather in five animal drug components of the Shenrongbian pill, identifying distinctive medulla cell shapes and hair cuticle patterns for each component.
13 citations
,
December 1983 in “Canadian journal of zoology” This study found that mesenchymal cell processes from the dermal papilla contact epithelial hair matrix cells through gaps in the basal lamina during hair matrix cell differentiation in mouse vibrissa follicles.
1 citations
,
August 2015 in “PubMed” This study discovered previously unknown structures in human hair shafts that may stabilize hair structurally and physicochemically.
4 citations
,
January 2019 in “Micron” This study observed that fetal hair follicle melanocytes varied in morphology and development stages, with melanosomes undergoing degradation into irregular pigment particles within keratinocytes.
43 citations
,
July 1994 in “Journal of Cell Science” This study found that the extraction-resistant structures in hair, feathers, and hagfish teeth are due to ε-(γ-glutamyl)lysine cross-linked proteins, emphasizing their role in maintaining the integrity of these materials.