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DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Statins may be linked to reproductive organ conditions, and their risks should be monitored.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.

In 2001, the FDA approved 12 new drugs for children to treat allergies, asthma, ADHD, birth control, and other conditions.

Natural products like propolis are causing more skin allergies, and certain skin treatments and medications have various side effects and risks.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Finasteride effectively treats BPH, but needs more trials to understand potential.

PGD2 stops hair growth and is higher in bald men with AGA.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.