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Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.

Different treatments for skin conditions were found to be effective and generally safe, with biologics recommended as the first choice for generalized pustular psoriasis.

Oral alitretinoin is effective for certain types of chronic hand eczema, with mild side effects.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

DNMT3A is crucial for healthy skin and hair growth.

Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.

Computational methods can speed up and improve the development and safety of herbal drugs.

Different nail disorders are treated by targeting their specific causes and using appropriate medications or protective measures.

Teriflunomide often causes mild to moderate hair thinning and loss in MS patients, which usually improves with or without treatment.

Tapinarof cream at 1% concentration is effective and better tolerated for treating atopic dermatitis than the 2% concentration.

595 nm pulsed dye laser is a cost-effective treatment for nonmelanoma skin cancer with a low recurrence rate.

The model and estimator can predict drug exposure in kidney transplant patients well.

The document lists various dermatology topics, treatments, and diagnostic methods.

Cicatricial alopecia causes permanent hair loss and is treated to relieve symptoms and stop progression.

Swimming in Lake Malawi can lead to schistosomiasis, hepatitis B vaccine might cause temporary hair loss, and certain drinks affect kidney stone risk.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

Male hormones can decrease the ability of immune cells to fight bacteria.

General Practitioners should know common skin problems in children, like infections and dermatitis.

Some new treatments for children's skin conditions are effective, but risks must be weighed.

Honokiol from Magnolia plants may be beneficial for treating various skin conditions and promoting hair growth.

Certain bacteria from the Citrullus colocynthis plant may be a new source of antibiotics to fight drug-resistant diseases.

The new nanofiber improves wound healing by releasing growth factors, reducing inflammation, and helping skin regeneration.

CuSi nanowires with NIR photothermal properties could effectively treat infected wounds and promote healing.

A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.

Thymoma-associated multiorgan autoimmunity can cause liver damage and affects multiple organs, with limited treatment options and a generally poor prognosis.

Some plants like Eclipta alba, Nardostachys jatamansi, and Rumex japonicus may help hair growth.

People with diabetes have a higher risk of skin infections and complications.

People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.