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Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Cathepsin L is essential for normal hair growth and development.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Male pattern hair loss could hint at androgens affecting COVID-19 severity.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Tempol is safe and may prevent hair loss from brain radiotherapy.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.