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HSD11b1 affects skin nerves and increases non-histaminergic itch.

A rare endocrine disorder, APS 1, was diagnosed in a 26-year-old man in Bangladesh.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

The document lists various dermatology topics, treatments, and diagnostic methods.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.