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The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.

Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

People with plantar corns and calluses may have a higher chance of having metabolic syndrome.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Lactate production is important for activating hair growth stem cells.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

High levels of androgens during early development may cause PCOS-like symptoms.

Early balding men may have insulin resistance, but lifestyle changes can help.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

People with psoriasis are more likely to have Metabolic Syndrome than those without psoriasis.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.