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Methotrexate is effective for treating rheumatoid arthritis but requires regular monitoring.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Placebo effects vary in hair loss trials, with split-scalp trials showing higher hair density after 6 months compared to whole-head trials.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.

Baricitinib helped a woman with severe hair loss regrow almost all her hair without side effects.

Treat hirsutism in premenopausal women with oral contraceptives and consider additional treatments if needed.

Finasteride improves hidradenitis suppurativa in children with no adverse effects.

Balneophototherapy effectively treats ichthyosis linearis circumflexa but may need ongoing treatment due to short remission.

Anifrolumab significantly improved skin lesions and hair regrowth in severe discoid lupus.

Tofacitinib helped regrow hair in a patient with severe hair loss and improved their quality of life without side effects.

Finasteride and metformin both help treat PCOS, but using them together works best.

The fractional carbon dioxide laser is a safe and effective treatment for alopecia areata and works better than betamethasone valerate cream alone.

Topical vitamin D is effective in treating vitiligo with few side effects.

Platelet Rich Plasma (PRP) shows promise for hair growth, ulcer healing, and skin rejuvenation, but more research is needed for consistent results and it's not suitable for people with certain blood conditions.

Tofacitinib is a promising treatment for children with rheumatic diseases.

Combining oral minoxidil with JAK inhibitors helps regrow hair in severe alopecia areata cases.

NB-UVB phototherapy is an effective and safe treatment for vitiligo, especially on hands and feet, and can be improved with tacrolimus.

Topical caffeine improves hair loss intensity, speed, and shedding, and works better with minoxidil/azelaic acid.

Effective acne treatment varies by type, with topical and oral medications showing strong evidence, and patient education and support are crucial.

The document concludes that proper diagnosis and individualized treatment are crucial for managing androgenization in women effectively.

Combining PRP therapy with minoxidil is the most effective treatment for hair loss in men.

Using a laser helmet with Minoxidil works better for male hair loss than Minoxidil alone, with no extra side effects.