research Regulation of BMP Signaling in Melanogenesis, Pigment Transfer, and Melanocyte Migration
BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
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900-930 / 1000+ results research Location and Fine Structure of Melanocytes in Human Fetal Scalp Hair Follicles
Melanocytes in the outer root sheath are likely stem cells that grow fast but stay immature.
research Mechanisms of Hair Graying: Incomplete Melanocyte Stem Cell Maintenance in the Niche
Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
research Morphologic Comparison of Cultured Human Epidermis Melanocytes, Amelanotic Melanocytes from Hair Follicles, and Mouse Melanoma Cells Observed by Atomic Force Microscope
Melanin granules can be expelled by exocytosis.
research Improved Cutaneous Wound Healing After Intraperitoneal Injection of Alpha-Melanocyte-Stimulating Hormone
Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.
research Assessing Auditory and Cochlear Function in Alopecia Areata Patients: Exploring the Link to Cochlear Melanocyte Damage
Alopecia areata may be linked to hearing problems, so patients should monitor their hearing.
research Betamethasone Activates Cultured Amelanotic Melanocytes Derived From Outer Root Sheath of Human Hair Follicle
Betamethasone activates and increases the growth of certain skin cells from hair follicles.
research Observation of Cultured Amelanotic Melanocytes from Hair Follicles by Atomic Force Microscopy
Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.
research On the Etiology of Vitiligo and Gray Hair
Melanocytes are destroyed by factors needed for melanin production, causing vitiligo and gray hair.
research Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging
As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
research Aging of the Hair Follicle Pigmentation System
Hair grays due to oxidative stress and fewer functioning melanocytes.
research Melanoblasts' Proper Location and Timed Differentiation Depend on Notch/RBP-J Signaling in Postnatal Hair Follicles
Notch/RBP-J signaling is crucial for proper placement and timing of melanocyte development in hair follicles.
research Three Streams for the Mechanism of Hair Graying
Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
research Hypopigmentation in Frontal Fibrosing Alopecia
FFA patients have fewer melanocytes and thinner skin compared to others.
research Preservation of Melanoblasts in White Hair Follicles of Segmental Vitiligo Lesions: A Preliminary Study
White hair follicles in vitiligo have fewer and less functional melanocytes.
research Site of Beige and Leaden Pigment Gene Expression Determined by Recombinant Embryonic Skin Grafts and Aggregation Mouse Chimaeras Employing Sash Homozygotes
Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.
research Hair Development and Langerhans Cell Migration During Human Embryogenesis
Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
research Segmental Vitiligo with Confetti-Like Peripheral Depigmentation
Segmental vitiligo affects hair follicle melanocytes, causing small, uniform depigmented spots.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Anatomy and Physiology of the Skin
The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Biology of Estrogens in Skin: Implications for Skin Aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research Stem Cell Dynamics in the Hair Follicle Niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research The Cell Biology of Human Hair Follicle Pigmentation
We need more research on human hair follicle pigmentation, not just mouse models.
research Gene Expression Profiling Gets to the Root of Human Hair Follicle Stem Cells
Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
research Characterization of the Serotoninergic System in the C57BL/6 Mouse Skin
Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
research Hardwiring Stem Cell Communication Through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research The Peripheral Clock Regulates Human Pigmentation
Certain genes control the color of human hair by affecting pigment production.
research Pharmacologic Interventions in Aging Hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans
Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.