Segmental Vitiligo with Confetti-Like Peripheral Depigmentation

    December 2018 in “ European Journal of Pediatric Dermatology/PD. European journal of pediatric dermatology ”
    L. Garofalo
    TLDR Segmental vitiligo affects hair follicle melanocytes, causing small, uniform depigmented spots.
    The document discussed a case of segmental vitiligo characterized by confetti-like peripheral depigmentation, where the depigmented spots were uniformly 1-2 mm in diameter and appeared to follow a follicular pattern. This pattern, along with the presence of inflammatory infiltrate at the follicular site, suggested that the depigmentation primarily affected hair follicle melanocytes. This finding aligned with previous reports on follicular vitiligo, a form of non-segmental vitiligo where hair follicle melanocytes are primarily and predominantly involved, contrasting with classical non-segmental vitiligo, which primarily affects epidermal melanocytes.
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