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Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Spironolactone most effective for hirsutism, but has side effects.

To diagnose hair loss, use a systematic approach including history, exams, and tests.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Doctors need to be better prepared to assess and treat obesity in patients.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Flutamide reduces hair growth better but has more side effects.

Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.

Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.