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Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Safflower oil nanoparticles can deliver hFGF10 to hair follicles, reduce inflammation, and potentially speed up hair growth in conditions causing hair loss.

Adipose-derived stem cells may help with hair loss, but more research is needed.

The compounds tested could potentially treat hair loss and alopecia.

Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.

Combining micro-needling, LED therapy, and growth factors with Finasteride® significantly improves hair growth.

Higher early lead exposure is linked to delayed puberty in girls.

Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.

Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.

Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Overexpressing Tβ4 in goats' hair follicles increases cashmere production and hair follicle growth.

Finasteride temporarily lowers male rat fertility without affecting libido.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.