March 2024 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï” This source highlights that topical retinoids, particularly adapalene and its combinations, are crucial in treating acne due to their rapid action, sustained effects, and good tolerability; the study underscores the enhanced patient adherence with Deriva C MS gel for acne treatment.
23 citations
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January 2011 in “International Journal of Immunopathology and Pharmacology” In this small study, topical minoxidil 2% was associated with an increase in normal hair shaft production in patients with Monilethrix without any reported side effects.
December 2024 in “PubMed” This study reports a case where cyclosporine effectively treated a 51-year-old woman with idiopathic follicular mucinosis resistant to other therapies, suggesting its potential as an option for refractory cases.
81 citations
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February 2000 in “Anti-cancer drugs” In this pilot study, Doxil at 60 mg/m² every 4 weeks showed activity against hormone-refractory prostate cancer but was limited by severe mucocutaneous toxicities.
May 2026 in “Reactions Weekly” 3 citations
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May 1994 in “Journal of Pharmacology and Experimental Therapeutics” This study found that minoxidil sulfate stimulates Cl channels, potentially depolarization-activated and outwardly rectifying, in eccrine clear cells, while minoxidil itself stimulates Ca-insensitive K currents.
September 2013 in “Neurodegenerative disease management” This review discusses teriflunomide as a disease-modifying therapy for multiple sclerosis and highlights its effectiveness and safety in clinical trials, but reports no new clinical results.
117 citations
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January 2003 in “Dermatology” This review discusses various treatments for moderate-to-severe acne, highlighting antibiotics, oral isotretinoin, and hormonal therapies, with a focus on resistance and emerging treatment options but reports no new clinical results.
September 2015 in “Photodiagnosis and Photodynamic Therapy”
6 citations
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December 2023 in “Lancet. Infectious diseases/The Lancet. Infectious diseases” This study found that treatment with the synbiotic SIM01 significantly alleviated multiple symptoms of post-acute COVID-19 syndrome compared to placebo, suggesting potential management benefits through gut microbiome modulation.
37 citations
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May 2016 in “JAAD case reports” This abstract describes monilethrix, an autosomal dominant genodermatosis with symptoms like hair fragility and keratosis pilaris, and does not report new experimental results.
January 2026 in “Nutrición Hospitalaria” In this study, researchers identified significant signals indicating previously unrecognized risks of lipid metabolism abnormalities for several drugs, urging the need for better monitoring and label updates.
April 1992 in “Current opinion in therapeutic patents” This study reports the development of novel 4-amido-Δ4,6-steroids as potential inhibitors of 5α-reductase, showing promising in vitro results for conditions like acne and benign prostatic cancer.
63 citations
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September 1987 in “Journal of Biological Chemistry” Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
October 2024 in “Iraqi postgraduate medical journal”
5 citations
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February 1997 in “Bioorganic & Medicinal Chemistry” This study found that among 17 beta-(N-ureylene-N,N'-disubstituted)-4-azasteroids, those with an N'-phenyl moiety were the most effective inhibitors of human type I 5 alpha-reductase.
July 1975 in “Archives of Dermatology” This article reports a case of macular amyloidosis associated with myelofibrosis with myeloid metaplasia, a combination not previously documented.
1 citations
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June 2013 in “Annals of the Rheumatic Diseases” This study observed that while all DMARD regimens had similar safety profiles, the leflunomide group experienced the most serious side effects leading to therapy discontinuation.
253 citations
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April 2014 in “Drugs” This review discusses the preclinical and clinical data on teriflunomide for multiple sclerosis, highlighting its selective action on immune cells without causing clinical immune suppression, and provides no new clinical results.
2 citations
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August 2024 in “Heliyon” This study concluded that Metformin may be suitable for prophylaxis or mild COVID-19, while a combination of Oseltamivir, Tamoxifen, and Dexamethasone could benefit moderate to severe cases, highlighting the need for more trials on other drug candidates.
September 2004 in “Inpharma Weekly”
February 2025 in “Pharmaceuticals” This study found that supplementing myo-inositol with microlipodispersed magnesium significantly improved acne and hirsutism in women with PCOS by reducing BMI, testosterone, and DHEAS levels, also enhancing quality of life without side effects, over 6 months.
July 2024 in “Journal of Investigative Dermatology” INTASYL is a promising, adaptable RNAi technology for treating skin cancers.
50 citations
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December 2017 in “Nanoscale” This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.
July 2026 in “Experimental Dermatology” In this study, researchers found that minoxidil sulfate enhances the anti-inflammatory effects of the JAK inhibitor baricitinib in alopecia areata, modulating inflammatory signals and preserving immune privilege features in human hair cells, which suggests potential benefits for combined therapy.
In this study, low-dose oral minoxidil was found to have a favorable safety profile for treating alopecia, with mostly mild side effects, in both general and hypertensive populations.
This study found that minoxidil nanoliposomes led to faster hair growth and reduced scalp bacteria in mice compared to free minoxidil.
6 citations
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January 2016 in “Bioorganic & Medicinal Chemistry Letters” This study reported that certain minoxidil conjugates, specifically those with spermine, methylenedianiline, and diaminofluorene, were able to induce differentiation in HL-60 acute myeloid leukemia cells without toxicity at a concentration of 10 μM.
1 citations
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June 2025 in “Asian Journal of Medical Sciences” In this study, MMF plus prednisolone was found to induce remission in 81% of patients with proliferative lupus nephritis, with fewer adverse effects such as alopecia and amenorrhea compared to CYC plus prednisolone, despite similar overall remission rates.
February 2023 in “Reactions Weekly”