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Flutamide caused damage to male rat reproductive organs and may affect fertility.

Most women with excessive hair growth have a hormonal cause.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Tamoxifen effectively treats gynecomastia without causing impotence.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.