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PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

PCOS often leads to sleep problems, especially obstructive sleep apnea, affecting overall health.

Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Docetaxel is safe and works well for older people with cancer, with manageable side effects.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Polymeric nanoparticles show promise for treating skin diseases.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

PGD2 stops hair growth and is higher in bald men with AGA.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Targeted cancer therapies often cause serious skin problems that need careful management.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.