March 2023 in “Medical lasers” Low-level laser therapy is a safe and effective treatment for hair loss.
40 citations
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July 2023 in “Clinical Pharmacology & Therapeutics” This review discusses the progress and challenges of targeted protein degradation therapies, highlighting the increasing number of degraders in cancer clinical trials and the limited diversity in targeted proteins, primarily focusing on those employing CRL4CRBN as the E3 ligase.
November 2025 in “The Journal of Immunology” This study observed that in human scalp hair follicles, BTNL2 expression is lower in stressed conditions, which correlates with increased cytotoxic activity by gamma/delta and CD8+ T cells, suggesting a possible role for BTNL2 in controlling immune responses relevant to alopecia areata.
April 2025 in “Journal of Applied Cosmetology” This study found that a combination of microneedling with growth factors and low-level light therapy led to visible hair regrowth without side effects in a patient with trichotillomania.
January 2024 in “Current research in toxicology” This review reports that thallium poisoning causes severe neurological damage, with early gastrointestinal symptoms and later neurological dysfunction, and highlights the importance of early diagnosis and Prussian blue as an effective antidote.
October 2025 in “Dermatologica Sinica” This study's network meta-analysis reported that botulinum injection combined with red laser and topical minoxidil is most effective for increasing hair density in androgenetic alopecia when using low-level laser therapy.
October 2023 in “Lithuanian University of Health Sciences” This study investigated the TG5 gene polymorphism in Lithuanian beef cattle, finding that the CC genotype is associated with higher productivity traits, such as live weight and carcass weight, compared to other genotypes, and noted a statistically significant impact on these traits.
January 2023 in “Dermatologic Therapy” This study evaluated a novel hand-held low-level light therapy device for treating mild-to-moderate acne, finding it significantly reduced inflammatory lesions and moderate acne severity without severe adverse reactions, while also reducing Cutibacterium acnes viability in vitro.
January 2026 in “Dermatologic Therapy” In this prospective study, researchers identified advanced age, androgenetic alopecia, high levels of lactate dehydrogenase and dihydrotestosterone, and low levels of adenosine triphosphate as independent risk factors for posttransplant telogen effluvium, offering insights for optimizing surgical strategies to reduce PTE risk.
1 citations
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January 2018 in “Journal of Neurology Research” This case report describes a 23-year-old male who developed leukopenia, thrombocytopenia, and rash associated with lamotrigine treatment, emphasizing the importance for clinicians to monitor for serious side effects, especially early in treatment.
This study found that low-level laser therapy significantly improved hair count and reduced hair loss in patients with alopecia areata of the scalp.
17 citations
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October 2006 in “Molecular and Cellular Endocrinology” This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
11 citations
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February 2020 in “Dermatology and therapy” This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.
January 2013 in “International Journal of Trichology” This case report describes a young girl with trichothiodystrophy and suggests the need for early diagnosis and multidisciplinary interventions for her educational challenges.
990 citations
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October 1999 in “Development” This study found that LEF1/TCF3 is necessary but not sufficient for TOPGAL activation in hair follicle development, indicating complex regulation in the skin.
This study conducted a comparative analysis of platelet rich plasma and low level laser therapy for androgenetic alopecia but does not present new clinical findings.
July 2024 in “Journal of Investigative Dermatology” ATR12-351 ointment safely delivers LEKTI protein to the skin, reducing enzyme activity in Netherton syndrome.
7 citations
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June 2010 in “Journal of The American Academy of Dermatology” This paper reports a single case of lichenoid cutaneous sarcoidosis that was unresponsive to standard treatments but showed marked improvement with the administration of oral tranilast.
33 citations
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March 2017 in “Dermatologic Surgery” In this clinical study, low-level laser therapy using the HANDI-DOME LASER device increased hair counts by 51% compared to controls, indicating its potential as a safe and effective treatment for androgenetic alopecia in women aged 18 to 60.
February 2024 in “Future science OA” This commentary highlights that the loss of the Y chromosome may disrupt UTY/TLE1-RUNX1 interactions, potentially impacting male hematopoietic cell development and leading to conditions like acute myeloid leukemia and T-cell acute lymphoblast leukemia.
45 citations
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December 2018 in “Lasers in Medical Science” In a 24-week randomized trial, this study found that the RAMACAP laser helmet significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, although limitations included a small sample size and potential issues with the control used.
2 citations
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January 2014 in “Journal of Cytology & Histology” In a mouse model, this study found that LAM/TSC cells invaded the uterus and increased angiogenesis, while anti-EGFR antibody and rapamycin effectively reduced cell presence and blood vessel proliferation.
July 2016 in “Chinese Journal of Dermatology” This study found that low-level laser therapy increased hair density in men with androgenetic alopecia, with even greater improvements seen when combined with finasteride.
This study found that low-level laser therapy may effectively stimulate hair growth in adults with androgenic alopecia, but further research is needed to confirm its long-term clinical effectiveness.
16 citations
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July 2021 in “American Journal of Medical Genetics Part A” This study identified novel LSS mutations implicated in hypotrichosis simplex with or without neurodevelopmental abnormalities, highlighting the need for careful evaluation of synonymous mutations' potential pathogenic effects.
3 citations
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December 2016 in “Springer eBooks” This study found that activating Toll-like receptor 3 in periodontal ligament stem cells enhanced their stem cell and immunosuppressive properties, potentially supporting effective periodontal tissue regeneration.
This study found that expressions of TLR-3, TLR-7, TLR-8, and TLR-9 were significantly higher in alopecia areata patients compared to healthy controls, indicating a potential role in disease autoimmunity.
2 citations
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September 2014 in “PubMed” This review discusses low-level laser or light devices as an alternative treatment for androgenetic alopecia and highlights the need for further research to compare their efficacy with existing therapies.
21 citations
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January 2019 in “Lasers in Medical Science” This review found that low-level laser therapy significantly increased hair density in adults with androgenic alopecia compared to sham treatments, with greater effects observed at lower treatment frequencies.
This study observed that low-level laser therapy (LLLT) increased cell viability in SARS-CoV-2-uninfected HEK293/ACE2 cells but did not improve viability in infected cells, suggesting mixed effects.