3 citations
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March 2024 in “Journal of the American Academy of Dermatology” Low-dose naltrexone helps improve symptoms and stabilize frontal fibrosing alopecia and lichen planopilaris.
3 citations
,
August 2021 in “Uro” This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.
This chapter provides dermatology trainees with insights on managing lichen planopilaris, emphasizing treating active disease to prevent further hair loss and recommending a tapered course of oral steroids for disease stabilization.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that spironolactone, a potassium-sparing diuretic with antiandrogenic activity, effectively improves hair density, reduces shedding, and stabilizes symptoms in female pattern hair loss, though symptoms often recur after discontinuation, suggesting the need for sustained therapy.
July 2025 in “Journal of Investigative Dermatology” Low-dose oral minoxidil is safe for the heart in the short term for hair loss patients.
11 citations
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January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.
February 2026 in “Expert Opinion on Pharmacotherapy” This study established consensus-based guidelines for using low-dose oral and topical minoxidil in managing pattern hair loss for patients undergoing hair transplant surgery, recommending specific dosages, monitoring procedures, and timing for initiation post-surgery.
9 citations
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May 2020 in “Journal of Pharmaceutical and Biomedical Analysis” This study developed an efficient LC-MS bioanalytical method to simultaneously quantify minoxidil sulphate and latanoprost in skin layers, supporting the formulation of topical treatments for androgenic alopecia.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This piece describes the EndoPump Male Enhancement supplement, which claims to enhance erections and libido, but notes that there is insufficient medical evidence supporting the efficacy of its ingredients for sexual health.
12 citations
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May 2005 in “Journal of the American Geriatrics Society” This case report describes successful treatment of valproate-induced hyperammonemia in a 79-year-old man using lactulose, marking the first such documented use for this condition.
May 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.
September 2022 in “JAAD Case Reports” This case report discusses rare but serious cardiac complications, including pericarditis and edema, observed with low-dose oral minoxidil for hair loss, highlighting the need for cautious prescribing, especially in high-risk patients.
June 2026 in “Annals of Medicine and Surgery” This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.
5 citations
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January 2021 in “Journal of The American Academy of Dermatology” This article reflects on the history and significance of the FDA's approval of topical minoxidil for treating androgenetic alopecia in men and women, dating back to 1988 and 1991 respectively.
33 citations
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May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
12 citations
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January 2020 in “Skin appendage disorders” Low-dose oral minoxidil effectively treats female hair loss with good safety.
18 citations
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January 1976 in “Drugs” New treatments improved blood pressure control in patients with resistant hypertension.
January 2004 in “Chinese Journal of Blood Purification” This study found that minoxidil is highly effective in managing severe hypertension in hemodialysis patients without affecting renal function, though it may cause hair growth.
4 citations
,
April 2009 in “Journal of Pain” Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
47 citations
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June 2011 in “Movement Disorders” The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
February 2025 in “Journal of the American Academy of Dermatology” Spironolactone helps prevent swelling caused by minoxidil in women with hair loss.
January 2020 in “Nihon rinsho hifukaikai zasshi” This case study observed that discontinuing risperidone reduced elevated prolactin levels and improved hair thinning in a 77-year-old woman, suggesting risperidone-associated telogen effluvium as a consideration in similar cases.
This review concludes that the global literature supports the efficacy and safety of lipidosterolic extract of Serenoa repens in treating lower urinary tract symptoms, comparable to alpha-blockers and 5α-reductase inhibitors.
105 citations
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December 2009 in “Archives of dermatology” This overview discusses primary cicatricial alopecias, focusing on lichen planopilaris, and highlights the challenges in treatment and the progressive nature of hair loss despite symptom management, without providing new clinical results.
2 citations
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October 2020 in “Journal of Pharmacology and Experimental Therapeutics” This study found that in a mouse model of bronchopulmonary dysplasia, minoxidil administered at 50 mg/kg/day did not impact lung development or inhibit lysyl hydroxylation.
2 citations
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July 2021 in “Journal of Cardiovascular Pharmacology” This study suggests that lisinopril's cardiometabolic effects are weaker in men with early-onset male-pattern baldness compared to those with normal hair growth.
3 citations
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January 2016 in “Respiratory Medicine Case Reports” This study suggests that the use of tamsulosin may worsen sleep-disordered breathing in some patients with obstructive sleep apnea being treated with CPAP.
36 citations
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March 2014 in “Annals of the Rheumatic Diseases” This study found that activating liver X receptors with an agonist reduced skin fibrosis in experimental models, particularly in inflammation-driven conditions, by inhibiting macrophage infiltration and interleukin-6 release.
9 citations
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December 2020 in “British Journal of Dermatology” This research letter reports that low-dose oral minoxidil improved hair density and length in children with loose anagen hair syndrome.
16 citations
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March 2006 in “The American journal of psychiatry” This report describes five cases where sudden akathisia occurred in female patients with bipolar disorder after a ziprasidone dose reduction, emphasizing potential unexpected side effects of second-generation antipsychotics.