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Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Taking 1 mg of finasteride daily can increase hair count and improve hair appearance, but it may have side effects on sexual function and a potential risk of prostate cancer. It may not be effective for postmenopausal women unless taken in higher doses.

The U.S. military's teledermatology program was effective in providing fast and successful skin care in remote locations, preventing unnecessary evacuations.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Mutations in certain receptors can cause diseases and offer new treatment options.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Oral bicalutamide is safe and effective for female hair loss.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Bicalutamide may be a promising alternative treatment for female pattern hair loss.

Clinicians should understand tattoos to manage health issues, as tattoos can cause complications and affect medical assessments.

The review suggests renaming two herbs to avoid confusion and recommends more research for safe use.