11 citations
,
August 2014 in “Current Urology Reports” This review discusses the known effects of medications for benign prostatic hyperplasia on sexual function and mechanisms of dysfunction but reports no new clinical results.
4 citations
,
October 2023 in “Fertility and Sterility” This review highlights potential negative impacts of certain medications on male fertility, such as hormonal disruption and germ cell toxicity, emphasizing the importance of clinicians being aware of these effects to advise on safer alternatives.
August 2024 in “medRxiv (Cold Spring Harbor Laboratory)” This study found that finasteride use is associated with both known and new adverse events, which vary by gender and age, as well as some events not previously listed in the drug insert.
14 citations
,
March 2001 in “Psychiatric Services” This article reviews changes in men's sexual health after midlife, exploring physiologic changes, psychological factors, and various treatment options, but it presents no new clinical results.
5 citations
,
September 2017 in “Plastic and Aesthetic Research” This study aimed to assess whether using minoxidil alongside nutritional cyclical supplements could boost hair regrowth without antiandrogens or enzyme blockers, focusing on hair root strengthening. Results are not reported.
3 citations
,
January 2019 in “International Journal of Trichology” This article reviews common malpractices in the treatment of hair and scalp disorders, attributing them to autistic-undisciplined thinking, and reports no clinical findings.
1 citations
,
July 2023 in “F&S Reviews” This review highlights that various commonly prescribed medications for chronic conditions may impact male fertility by affecting hormone secretion, sperm production, ejaculation, erectile function, and libido, although conclusive evidence is limited to specific drug groups.
November 2023 in “Materials Today Bio” This article discusses photobiomodulation as a potential adjunct to hair follicle organoid culture for androgenic alopecia, reporting no new results and suggesting further study is needed.
April 2026 in “Brain Sciences” This pharmacovigilance study analyzed FAERS data and found that finasteride is more frequently associated with neuropsychiatric reactions like depression and suicide risk, especially in younger men using it for alopecia, compared to dutasteride.
1 citations
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October 2022 in “Springer eBooks” This review discusses the roles of hormonal pathways in regulating male sexual function, particularly highlighting the impact of testosterone, and reports no new research findings.
16 citations
,
November 2021 in “Antioxidants” This review examines the role of oxidative stress in male hypogonadism associated with noncommunicable chronic diseases and discusses various management strategies, but it presents no new clinical findings.
March 2026 in “The Aging Male” This retrospective pharmacovigilance study reviewed adverse event reports from 2004 to 2025 for drugs treating benign prostatic hyperplasia, identifying distinct safety signals for α1-blockers, 5ARIs, and PDE5I, including some potential new adverse events that require further investigation.
April 2021 in “IntechOpen eBooks” This article discusses the need to investigate long-term effects of androgen manipulations independently of current levels, referencing Post-finasteride Syndrome as a relevant clinical example, and reports no new results.
4 citations
,
January 2015 in “Pharmacology” This report describes a case where a food supplement containing Serenoa repens extract was associated with hot flashes and menarche in a 10-year-old girl being treated for hirsutism.
February 1999 in “Strength and Conditioning Journal” Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.
3 citations
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November 1999 in “Journal of Cutaneous Medicine and Surgery” AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
March 2026 in “Canadian Urological Association Journal” This study observed that complementary and alternative medicine, often marketed to men as ways to enhance "optimization," "recovery," and "vitality," has become mainstream, with many believing in its benefits for testosterone, erections, libido, hair loss, and sperm quality.
April 2025 in “Physical and Engineering Sciences in Medicine” In this study, the analysis of PCOS subreddit data revealed that lifestyle changes and supplements were perceived positively for managing PCOS symptoms, while contraceptives were often linked with negative experiences, except when they included anti-androgenic progestins.
41 citations
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November 2003 in “Annals of the New York Academy of Sciences” This article discusses the complexities of androgen and antiandrogen therapies in women, detailing diagnostic measures, the effects on libido, and the potential benefits of new progestins with antiandrogenic properties, but presents no new empirical findings.
10 citations
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January 2010 in “PubMed” This article reviews current hair loss treatments, proposing a hypothesis that a combination of drugs, supplements, and therapies may effectively manage hair loss, but presents no new clinical results.
September 2025 in “Cureus” In this case report, a male patient with hair loss showed unusually high testosterone levels without other symptoms or supplement use; follow-up testing revealed normal levels, showcasing the importance of considering testosterone-protein binding differences and using equilibrium dialysis for accurate assessment.
This review found that various treatments like finasteride, minoxidil, and platelet-rich plasma, combined with supplements, showed positive responses in combating androgenetic alopecia. The study specifically highlighted finasteride's effectiveness in increasing hair growth, with different dosages yielding notable improvements in both men and pre-menopausal women.
October 2024 in “Open Repository of the University of Porto (University of Porto)” In this report, the author shares experiences from a six-month curricular internship, highlighting activities such as arterial pressure monitoring in a community pharmacy and addressing off-label rituximab use at a hospital, alongside discussions of hair loss treatments and nutritional supplementation for dysphagia in the elderly.
36 citations
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January 2014 in “Evidence-based Complementary and Alternative Medicine” This study found that men with androgenetic alopecia treated with pumpkin seed oil for 24 weeks experienced a notable 40% increase in hair count compared to a 10% increase with a placebo.
228 citations
,
February 2003 in “Urology” This article discusses the side effects of androgen deprivation therapy for nonmetastatic prostate cancer, highlighting the need for clinical trials to systematically study these effects.
16 citations
,
July 2012 in “The New England Journal of Medicine” This case report describes a 27-year-old man hospitalized with fatigue, myalgias, weakness, profound weight loss, and abnormal liver function, leading to a diagnosis after chest imaging revealed pneumomediastinum.
71 citations
,
September 2007 in “Cancer” This review discusses various prostate cancer prevention strategies and reports no new clinical results; the authors highlight the need for ongoing research in this area.
February 2026 in “Frontiers in Endocrinology” In this case study, a woman with congenital adrenal hyperplasia experienced substantial improvement in musculoskeletal and neurobehavioral symptoms after low-dose testosterone therapy, highlighting its potential role in managing chronic glucocorticoid overtreatment effects.
95 citations
,
February 2018 in “Dermatology and Therapy” This review discusses the role of nutraceuticals in combating skin aging but reports no new clinical results, focusing on their mechanisms of action and potential effectiveness for dermatologists.
6 citations
,
September 2005 in “Expert Opinion on Pharmacotherapy” This review discusses the role of androgens in women's sexual health and highlights the need for further research on androgen replacement therapy to optimize quality of life, but reports no new clinical results.