What Do Users in a Polycystic Ovary Syndrome (PCOS) Forum Think About the Treatments They Tried: Analyzing Treatment Sentiment Using Machine Learning

April 2025 in “ Physical and Engineering Sciences in Medicine ”

Rebecca H K Emanuel, Paul D. Docherty, Helen Lunt, Rebecca E. Campbell

polycystic ovary syndrome PCOS inositol combined oral contraceptive pills anti-androgenic progestins intermittent fasting birth control pills

Studysummary In this study, the analysis of PCOS subreddit data revealed that lifestyle changes and supplements were perceived positively for managing PCOS symptoms, while contraceptives were often linked with negative experiences, except when they included anti-androgenic progestins.

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research International PCOS Guideline Clinical Research Priorities Roadmap: A Co-Designed Approach Aligned With End-User Priorities in a Neglected Women's Health Condition

15 citations , November 2024 in “EClinicalMedicine”

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Efficacy and Safety of Anti-Androgens in the Management of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

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This study reported that anti-androgens combined with lifestyle modifications were more effective than metformin and lifestyle in reducing hirsutism and certain hormonal measures in women with PCOS, but they were not more effective than a placebo combined with lifestyle changes.

Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome

research Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome

8 citations , August 2023 in “The Journal of Clinical Endocrinology and Metabolism”

This study provided updated international guidelines for assessing and managing polycystic ovary syndrome, emphasizing evidence-based recommendations and acknowledging the low to moderate quality of existing evidence.

research The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Systematic Review

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This study concluded that both oral and topical spironolactone effectively treat androgenetic alopecia, with topical administration being safer and suitable for any gender, especially when combined with minoxidil.

research Hyperandrogenism and Menstrual Imbalance Are the Best Predictors of Metformin Response in PCOS Patients

9 citations , January 2022 in “Reproductive Biology and Endocrinology”

This study aimed to identify reliable predictors for the effectiveness of metformin therapy in weight loss and reduction of plasma androgen levels in PCOS women, highlighting the unpredictability of response to treatment.

research The Challenges with Managing Polycystic Ovary Syndrome: A Qualitative Study of Women’s and Clinicians’ Experiences

21 citations , May 2021 in “Patient education and counseling”

This study explored the challenges faced by both clinicians and women with polycystic ovary syndrome in managing the condition, highlighting issues with treatment options, misinformation, and differing expectations in care.

research Natural Hair Supplement: Friend or Foe? Saw Palmetto, A Systematic Review in Alopecia

8 citations , January 2020 in “Skin appendage disorders”

This review found that supplements containing saw palmetto may improve hair quality and density in patients with androgenetic alopecia and telogen effluvium, but more large-scale RCTs are needed for conclusive evidence.

research Complementary and Alternative Treatments for Alopecia: A Comprehensive Review

40 citations , August 2018 in “Skin appendage disorders”

This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.

Ethnicity, Obesity, and the Prevalence of Impaired Glucose Tolerance and Type 2 Diabetes in PCOS: A Systematic Review and Meta-Regression

research Ethnicity, Obesity, and the Prevalence of Impaired Glucose Tolerance and Type 2 Diabetes in PCOS: A Systematic Review and Meta-Regression

189 citations , March 2018 in “Human Reproduction Update”

This study reported that women with polycystic ovary syndrome had a higher prevalence of impaired glucose tolerance and type 2 diabetes, with variations influenced by ethnicity and obesity.

research Spearmint Herbal Tea Has Significant Anti-Androgen Effects in Polycystic Ovarian Syndrome: A Randomized Controlled Trial

90 citations , July 2009 in “PTR. Phytotherapy research/Phytotherapy research”

In this study, spearmint tea significantly reduced testosterone levels and improved self-reported hirsutism in women with PCOS, but did not change objective hair growth scores over the short trial period.