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Insulin resistance is found in 20% of Thai women with PCOS, with age, waist size, skin changes, and abnormal blood fats increasing the risk.

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

Melatonin improved cashmere production in goats during the first cycle but had no lasting effects on the next cycle.

Lower melatonin levels are linked to more skin aging.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

Anovulatory PCOS patients are younger with longer cycles and higher blood pressure and hormone levels.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Hirsutism is when women have too much hair growth, often due to a bit more androgen hormones and sensitive skin.

Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.

Polycystic Ovary Syndrome (PCOS) is common in women with conditions like anovulation, hirsutism, hair loss, and type 2 diabetes, and it can lead to health risks like heart disease, obesity, insulin resistance, and depression. Non-Classic Congenital Adrenal Hyperplasia (NC-CAH) is also discussed.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.

Healthy diet and exercise are important for women with PCOS to manage weight and metabolic issues, and supplements like omega-3, vitamin D, and inositol may help.

Acanthosis nigricans in teenage girls with PCOS is a sign of obesity, not insulin resistance or glucose intolerance.