16 citations,
January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
11 citations,
November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
2 citations,
May 2009 in “Hair transplant forum international” Keeping the head elevated for 1.5 days after hair transplant surgery helps prevent facial swelling.
July 2024 in “Behavioural Brain Research” Long-term finasteride treatment reduces depression and brain issues in obese male rats.
April 2018 in “Gynäkologische Endokrinologie” Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.
211 citations,
May 2013 in “Journal of Nutrition Health & Aging” MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
91 citations,
November 2007 in “European journal of endocrinology” Metformin helps with PCOS symptoms no matter the patient's initial insulin resistance or weight.
61 citations,
February 2001 in “American Journal of Obstetrics and Gynecology” Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.
37 citations,
May 2004 in “Multiple Sclerosis Journal” The article concludes that proper injection techniques and patient education can prevent serious skin reactions from multiple sclerosis medications.
34 citations,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
24 citations,
November 2015 in “Experimental Cell Research” Sebum from sebocytes is important for skin health and linked to conditions like acne and hair loss.
19 citations,
July 2015 in “Journal of inherited metabolic disease” Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.
16 citations,
February 2016 in “Gynecological Endocrinology” Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.
16 citations,
April 2012 in “Gynecological Endocrinology” Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.
11 citations,
October 2018 in “Hormone and Metabolic Research” Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
11 citations,
March 2016 in “Translational Andrology and Urology” Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
11 citations,
July 2003 in “The Nurse practitioner” New treatments for PCOS focus on managing symptoms and improving fertility.
3 citations,
January 2013 in “Egyptian Liver Journal” Many young Egyptian women with PCOS also have fatty liver disease, especially if they are overweight and insulin resistant.
2 citations,
December 2013 in “Cancer research” Enobosarm may effectively treat androgen receptor-positive breast cancer with fewer side effects.
1 citations,
December 2021 in “Cureus” Overweight PCOS patients often have skin issues like acne, but all PCOS patients should get lifestyle advice.
September 2024 in “Chemico-Biological Interactions” Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.
Women with Polycystic Ovary Syndrome (PCOS) have a higher risk of developing type 2 diabetes due to insulin resistance.
December 2022 in “Türk biyokimya dergisi” The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
September 2018 in “Fertility and Sterility” African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.
February 1999 in “Strength and Conditioning Journal” Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.
March 2023 in “Archives of Physical Medicine and Rehabilitation” Testosterone and finasteride improve body composition in men with spinal cord injury.
29 citations,
October 2020 in “eLife” Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
5 citations,
March 2018 in “Clinics in Dermatology” PRP injections and scalp lifting together improve hair thickness and growth in hair loss patients.
159 citations,
August 2010 in “British journal of dermatology/British journal of dermatology, Supplement” Hydroxychloroquine effectively reduces symptoms of frontal fibrosing alopecia, especially in the first 6 months.