This dissertation describes using skull bone for upper jaw reconstruction, leading to less pain and the possibility of immediate implant placement compared to traditional methods.
In this study, researchers observed that oncogenic HrasG12V in single murine epidermal cells leads to an initial increase in progenitor cell renewal, but ultimately results in balanced cell fate choices that limit clone growth.
This study found that bovine slick mutations may enhance heat stress responses in mice but do not lead to the expected hair phenotype changes.
This review highlights the potential analytic interference of high-dose biotin with immunochemical tests, which may lead to diagnostic errors and suggests pausing biotin consumption before laboratory testing.
September 2018 in “Research in medical & engineering sciences” This personal account describes the author's experience of being scammed by a fraudulent digital marketing company promising sales leads from a health marketing campaign.
April 2018 in “Journal of Investigative Dermatology” This study found that the loss of transcription factor Ovol2 in epidermal and hair follicle stem cells leads to migration defects, which are partially improved by deleting the EMT-inducing Zeb1.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that mitochondrial dysfunction might contribute to the pathogenesis of Lichen planopilaris by triggering a metabolic shift that leads to chronic inflammation and hair follicle damage.
This study developed and validated an optimized culture method for dermal papilla cells, leading to the establishment of an immortalized cell strain called iDP6, which resembles primary DP cells in key characteristics.
September 2017 in “Journal of Investigative Dermatology” LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.
August 2017 in “ARSHI Veterinary Letters” This case report describes a 10-year-old Shih Tzu diagnosed with hyperadrenocorticism, leading to the management of skin issues which initially improved but was followed by neurological symptoms, prompting euthanasia.
April 2017 in “Journal of Investigative Dermatology” This study identified that dominant mutations in the KLHL24 gene cause epidermolysis bullosa through dysregulated autoubiquitination, leading to excessive degradation of keratin 14.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” This study highlights the roles of dietary nutrients in maintaining skin health, noting that shortages can lead to hard-to-detect dysfunctions, and suggests that nutraceuticals may help address these nutritional gaps and improve skin-related issues linked to aging and dermatoses.
January 2017 in “Elsevier eBooks” Congenital Adrenal Hyperplasia is mainly caused by enzyme deficiencies, leading to varying symptoms like hormone imbalances and physical changes.
April 2012 in “Cancer Research” In this study, mouse models with EGFR deficiency showed that disrupted hair follicle cycling leads to increased mast cell numbers and inflammation, suggesting EGFR's role in managing hair cycle transitions and preventing folliculitis.
January 2012 in “Modern Plastic Surgery” This review discusses Toe Tourniquet Syndrome, a frequently misdiagnosed condition that can lead to necrosis if untreated, and calls for increased clinician awareness, but reports no new clinical findings.
June 2011 in “CRC Press eBooks” Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.
January 2011 in “Reactions Weekly” Long-term use of minoxidil may cause hair follicles to transform into noticeable terminal hairs, leading to trichostasis spinulosa.
July 2008 in “Planta Medica” This study found that Acanthus montanus leaves' aqueous extract is a developmental toxicant in rats, leading to several adverse effects on offspring when used during pregnancy.
January 2008 in “대한미용학회지” This study reports that prolonged UV irradiation causes progressive damage to the hair's keratin structure, leading to increased surface roughness, cuticle destruction, and decreased tensile strength in young women’s hair.
The authors of this study concluded that higher calcium levels in hair may indicate early metabolic changes leading to osteopenia or osteoporosis in menopausal women, even before detectable by standard DEXA imaging.
January 2005 in “Journal of Marine Fisheries” Female pattern hair loss is caused by genetics and hormones, leading to hair thinning in women.
January 2005 in “Chinese Journal of Integrated Traditional and Western Nephrology” This study found that systemic lupus erythematosus in aging patients often presents with atypical clinical manifestations, leading to more frequent misdiagnosis, yet these patients may respond better to treatment.
January 2004 in “Giornale di Metafisica: revista bimestrale di filosofia” This study suggests that increased Wnt signaling may promote excessive differentiation of melanocytes, leading to exhaustion of melanocyte stem cells and hair graying in aged mice.
January 2004 in “Laboratory Animal Science and Administration” This study found that the hairless mutant gene in C 57BL/6 mice affects the hair follicle cycle and leads to early thymus degeneration and distinct skin changes.
December 1997 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study concluded that low energy laser therapy may effectively complement classical treatment for scalp alopecia, leading to faster results, although long-term maintenance still requires ongoing classical therapy.
October 1982 in “American Journal of Nursing” Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
September 1961 in “Archives of Dermatology” This correspondence questions the assertion in a 1961 article that lichen sclerosus et atrophicus does not lead to carcinoma, citing a case contrary to the author's claim.
January 2022 in “Current Enzyme Inhibition” This study found that two novel nonsteroidal derivatives inhibited specific enzymes in vitro and in vivo, leading to dihydrotestosterone accumulation in androgen-dependent glands, suggesting potential therapeutic use for mood improvement in the elderly.
January 2003 in “Journal of Dermatology and Venereology” Female pattern hair loss in women is caused by hormones and genetics, leading to hair thinning, with various treatments available.
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October 2012 in “Cellular and Molecular Life Sciences” This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.