February 1990 in “PubMed” This study suggests that human hair follicle cells and epidermal keratinocytes differ in their degree of keratinization and other characteristics when cultured on mixed collagen membranes.
March 2018 in “Ayurline: IJ-RIM” In this study, Ayurvedic Keshya gel, formulated with specific herbs and essential oils, was found to be effective in reducing hair fall and improving hair quality in both men and women.
January 2026 in “Frontiers in Bioscience-Landmark” This study reported that, in a laboratory setting, araliadiol derived from Centella asiatica activated antioxidant pathways, mitigating urban particulate matter-induced oxidative stress and skin damage.
February 2026 in “Frontiers in Immunology” In this study analyzing FDA data, researchers found that tralokinumab was associated with higher reports of conjunctivitis and keratitis compared to dupilumab, while dupilumab had more frequent injection site reactions, highlighting potential risks for clinical monitoring in atopic dermatitis treatments.
2 citations
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February 2021 in “FEBS open bio” In this study, transfection experiments showed that mutations in the K85 gene affect filament formation with K35, which may impact hair formation related to ectodermal dysplasia.
27 citations
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May 2004 in “Journal of Investigative Dermatology” 27 citations
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February 2021 in “Clinical and Experimental Dermatology” This review synthesizes recent studies and suggests that Curcuma species may provide various dermatological benefits, but further research is needed to determine optimal delivery methods and dosages.
January 1995 in “Skin Cancer” This review discusses the cell biological characteristics of the outer root sheath of normal human hair follicles and highlights some similarities and differences with trichilemmal tumors, but reports no new results.
19 citations
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March 2013 in “Biology Letters” This study found that the main structural proteins of tree frog toe pads, which aid in their adhesive properties, are alpha keratins that have evolutionary origins in early tetrapods.
12 citations
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January 2014 in “Cell structure and function” This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.
13 citations
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January 2018 in “Advances in experimental medicine and biology” 4 citations
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November 2024 in “BMC Ophthalmology” This case report describes a rare instance of a giant and atypical proliferating pilomatrixoma on the eyelid, successfully treated with surgical excision, with no recurrence observed after one year, emphasizing the need to excise and histologically evaluate enlarging periocular masses to rule out malignancy.
January 2024 in “Toxicologic Pathology” This review outlines the structure and functions of the skin, emphasizing its role as a physical and immune barrier, its moisture regulation, the influence of its microbiome, and the supportive functions of its layers and adnexa.
The best mix of propylene glycol and sorbitol was found for a cream to prevent hair loss using saw palmetto extract.
3 citations
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January 1998 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” This study used rapid-freezing immunocytochemistry to successfully map the ultrastructural localization of hair keratins in human scalp hair, primarily finding them in macrofibrils in the cortex and endocuticle.
December 2009 in “Journal of Veterinary Clinics” The authors diagnosed a 5-year-old Pekinese dog with keratoacanthoma with granulomatous inflammation, and the mass did not recur 5 months after surgical removal.
31 citations
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May 2009 in “Bijdragen tot de Dierkunde” This study suggests that reptilian claws grow differently from mammalian claws, with continuous epidermal growth rather than a proximal matrix zone for cell proliferation.
6 citations
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July 2011 in “British Journal of Dermatology” This paper reports a case of sebaceous carcinoma developing at the site of chronic candidiasis in a patient with keratitis–ichthyosis–deafness syndrome, without presenting new generalizable findings.
3 citations
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December 2021 in “Materials today communications” This study found that a keratin film made from human hair supports enhanced cell proliferation and viability compared to collagen I, suggesting potential for cell culture applications.
18 citations
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January 1992 in “Dermatology” This case report details atrichia with papular lesions in a 4-year-old girl, highlighting specific histological findings on her scalp and other affected areas.
14 citations
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March 2000 in “Journal of Zoo and Wildlife Medicine” This study identified a new Demodex species causing demodicosis in a zoo koala, successfully treated with daily oral ivermectin.
52 citations
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April 2012 in “Journal of Investigative Dermatology” This study found that KRTAP2 proteins predominantly express in the hair shaft cortex of humans, interact with hair keratins, and play crucial roles in hair shaft keratinization.
40 citations
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May 2010 in “American Journal of Clinical Dermatology” This study reports that four Indian patients with acne keloidalis nuchae also exhibited acanthosis nigricans, suggesting a potential link to metabolic syndrome, though further research is needed to confirm this association.
5 citations
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December 2002 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This study suggests that keratinocytes in skin and mucous membranes might be involved in prion disease transmission due to their expression of PrPc, potentially serving as an entry point for prions.
December 2012 in “Journal of undergraduate research in Alberta” This study suggests that primary cilia may enhance the proliferation of skin-derived precursors when combined with lithium chloride and platelet-derived growth factor, potentially targeting them for stem cell-based therapies.
88 citations
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January 1981 in “British Journal of Dermatology” This study describes a new method for culturing human hair follicle cells, achieving 70% successful growth of keratinocyte colonies using a bovine eye lens capsule substrate.
92 citations
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January 2012 in “International Journal of Biological Sciences” This article proposes an updated naming system for keratin-associated proteins and genes, aiming to improve data storage and retrieval by including species information and genetic variation.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and evaluated a hair serum using Murraya koenigii and Clitoria ternatea extracts, finding that the F3 formulation had strong antifungal activity and was effective in dandruff management, suggesting potential benefits for scalp health.
13 citations
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August 1999 in “Journal of Investigative Dermatology” This study found that bikunin is expressed in human keratinocytes and may play a role in regulating keratinocyte function during mitosis or inflammation.