April 2025 in “Dermatology Practical & Conceptual” UV-enhanced trichoscopy helps diagnose hair shaft disorders like pili annulati.
1 citations
,
June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.” This study found that chemically modifying human hair through esterification or disulfide reduction and alkylation affects the hair's viscoelastic properties, including stability, integrity, and response to moisture.
31 citations
,
December 2010 in “Journal of the American Academy of Dermatology” This study reports that structural abnormalities in the inner root sheath of hair follicles may cause the hair shaft to be loosely attached in patients with loose anagen hair syndrome.
12 citations
,
January 2014 in “Cell structure and function” This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.
3 citations
,
February 2011 in “Journal of Biomedical Research/Journal of biomedical research” This study identified a novel mutation, R430Q in the KRT86 gene, in a Han family with monilethrix, which may contribute to the disease's pathogenic mechanism.
This chapter reviews the clinical and morphological diagnostic features of various hair dysplasias, including atypical pili torti, pseudomonilethrix, and trichothiodystrophy, and reports no new results.
This study examines the structure of the "sinuskissen" in cat hair follicles, revealing it as a loose connective tissue susceptible to changes in aqueous flow, and describes its variable three-dimensional shapes.
February 2025 in “Indian Dermatology Online Journal” This case report describes a rare occurrence of pincer nail deformity in a patient with systemic lupus erythematosus, potentially linked to Raynaud's phenomena as a contributing factor.
20 citations
,
July 1988 in “Clinics in dermatology” This article reviews the current practices and interpretations of research data on permanent waving and hair straightening, but does not present any new research findings.
January 2025 in “Kuwait Journal of Science” In this study, researchers sequenced the KRT71 gene in 102 dromedary camels to find genetic polymorphisms linked to hair shape, identifying 17 variants but none that fully explained hair shape variations, suggesting other genes may also play a role.
50 citations
,
July 2008 in “British Journal of Dermatology”
December 2023 in “Data in Brief” In this study, the researchers conducted tensile tests on individual curly human hair fibers sourced from a female donor and found distinct mechanical properties under various conditions, including different strain rates and temperatures, both dry and in saline immersion.
January 2019 in “Durham e-Theses (Durham University)” This study found that JNK plays a dominant role in hair follicle matrix density-dependent proliferation and differentiation, suggesting that collagen bundling affects keratinocyte dynamics.
186 citations
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December 2012 in “Current opinion in cell biology” This review discusses the recent advancements in understanding how keratins influence cytoarchitecture, cell dynamics, and disease processes but reports no new clinical results; the authors highlight its roles in development and diseases like cancer.
19 citations
,
February 2016 in “Journal of Biological Chemistry” In this study, researchers observed that knocking out KCNQ3 in mice increased firing frequencies in response to stimuli, particularly at slow mechanical indentation velocities, indicating a role in mechanosensory neuron sensitivity.
1 citations
,
December 2015 in “International journal of pediatric research” This review discusses the occurrence of hair tourniquets in children and adolescents, reporting no new clinical results but highlighting case variations by age and affected body part.
7 citations
,
August 2008 in “Cases Journal” This article reports a case of a 14-month-old child with a constriction ring syndrome caused by tightly wrapped hair, highlighting the importance of early recognition and treatment to prevent serious complications.
52 citations
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May 2006 in “Journal of Structural Biology” This study identified two key pentapeptide quasi-repeats in human keratin-associated proteins, which are similar to motifs found in sheep wool.
4 citations
,
March 1999 in “International Journal of STD & AIDS” This report details a case of severe recurrent bacterial vaginosis in a woman with Netherton's syndrome.
August 2026 in “Dermatology and Therapy” In this study, researchers identified elongated corkscrew hairs as a new trichoscopic pattern in immunosuppressed adults with chronic endothrix tinea capitis, which may help in earlier diagnosis and targeted mycological investigation.
41 citations
,
October 2008 in “The American journal of pathology” This study found that reducing BMP signaling in mouse nipple epithelia, achieved through Noggin overexpression, can convert them into hairy skin with pilosebaceous units.
1 citations
,
October 1993 in “PEDIATRICS” This article recounts a series of "hair burning syncope" cases in black girls experiencing seizures during hair grooming with hot irons, without presenting new research findings.
62 citations
,
December 2008 in “Journal of structural biology” This study found that in naturally curved human scalp hairs, distinct arrangements of cell types on either side of the hair fiber contribute to its curvature.
2 citations
,
December 2013 in “The Journal of Dermatology” This article is a letter to the editor about onychogryphosis associated with an elastic wire, and reports no new research findings.
41 citations
,
July 2020 in “Colloids and surfaces. B, Biointerfaces” This study suggests that adjusting the ratios of keratin-associated proteins to keratin intermediate filaments can create keratin/chitosan hydrogels with more consistent gel properties for tissue engineering.
1 citations
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August 2014 in “OhioLink ETD Center (Ohio Library and Information Network)” This research provides insights into how keratin hydrogels, modified to control disulfide crosslinking, may function as a treatment platform for bone injuries.
1 citations
,
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that knocking out vinculin in mouse skin disrupts bulge stem cell quiescence by impairing force generation and mechanical stability of adherens junctions.
42 citations
,
September 2003 in “Journal of Investigative Dermatology” A missing mK6irs1 gene causes hair loss in mice.
84 citations
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April 2002 in “Archives of Dermatology” This study found that a keratin mutation may cause diffuse partial woolly hair associated with loose anagen hair syndrome in some families, but other genetic factors could play a role in different cases.
3 citations
,
August 2018 in “Journal of Structural Biology” KAP8.1 protein is crucial for hair structure and interacts with keratin 85.